In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland

Cell-based studies previously showed that the ATP-binding cassette transporter A1 (ABCA1) transfers cholesterol across mammary epithelial cells (MEC). Data for phospholipid transport are lacking, and it is unclear from which cellular source the transported cholesterol stems, whether this transport a...

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Veröffentlicht in:	Molecular and cellular endocrinology 2017-01, Vol.439, p.35-45
Hauptverfasser:	Ontsouka, Corneille Edgar, Huang, Xiao, Aliyev, Eldar, Albrecht, Christiane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoprotein A-1 Apolipoprotein A-I - metabolism ATP Binding Cassette Transporter 1 - metabolism Biological Transport - drug effects Biological Transport - genetics Cattle Cell Line Cholesterol Cholesterol - metabolism Efflux Epithelial Cells - drug effects Epithelial Cells - metabolism Female Gene Expression Regulation - drug effects Homeostasis - drug effects Hormone Hormones - pharmacology Mammary Glands, Animal - cytology Mammary Glands, Animal - metabolism Membrane Transport Proteins - metabolism Phospholipid Phospholipids - metabolism Regulation RNA, Messenger - genetics RNA, Messenger - metabolism Signal Transduction - drug effects Signal Transduction - genetics Transport
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