A preliminary study searching for the right dose of tacrolimus in very young (≤4 years) renal transplant patients

Objectives The Radboudumc Amalia Children's hospital in the Netherlands has a programme for renal transplantation in children aged ≤4 years. Children receive chronic corticosteroid sparing immunosuppressive therapy that consists of tacrolimus and mycophenolate mofetil. This work aimed to descri...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2016-11, Vol.68 (11), p.1366-1372
Hauptverfasser:	Martial, Lisa C., Verstegen, Ruud H.J., Cornelissen, Elisabeth A.M., Aarnoutse, Rob E., Schreuder, Michiel F., Brüggemann, Roger J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Area Under Curve Calcineurin Inhibitors - administration & dosage Calcineurin Inhibitors - adverse effects Calcineurin Inhibitors - blood Calcineurin Inhibitors - pharmacokinetics Child, Preschool children Drug Administration Schedule Drug Dosage Calculations Humans immunosuppressant Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - adverse effects Immunosuppressive Agents - blood Immunosuppressive Agents - pharmacokinetics Infant Kidney Transplantation - adverse effects Netherlands pharmacokinetics Tacrolimus - administration & dosage Tacrolimus - adverse effects Tacrolimus - blood Tacrolimus - pharmacokinetics therapeutic drug monitoring transplantation Transplants & implants
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