A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children

Objective To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. Study design We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of ag...

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Veröffentlicht in:The Journal of pediatrics 2016-12, Vol.179, p.139-143.e1
Hauptverfasser: Chogle, Ashish, MD, MPH, Velasco-Benitez, Carlos A., MD, Koppen, Ilan J., MD, Moreno, Jairo E., MD, Ramírez Hernández, Carmen R., MD, Saps, Miguel, MD
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container_end_page 143.e1
container_issue
container_start_page 139
container_title The Journal of pediatrics
container_volume 179
creator Chogle, Ashish, MD, MPH
Velasco-Benitez, Carlos A., MD
Koppen, Ilan J., MD
Moreno, Jairo E., MD
Ramírez Hernández, Carmen R., MD
Saps, Miguel, MD
description Objective To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. Study design We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants & Toddlers. Results Parents of 1231 subjects completed the questionnaires; 48 children were excluded due to presence of organic diseases and being older than 48 months of age. Four hundred eighty children (40.5%) were diagnosed with at least 1 FGID according to the Rome III diagnostic criteria (49% female, median 12 months). Functional constipation was the most commonly diagnosed disorder in infants (up to 12 months of age) and children of ages 13-48 months (16.1% and 26.8%, respectively). Analysis revealed that the prevalence of FGID was significantly greater in children who were the only child in the family ( P  = .003), children who were first-born ( P  = .007), and children with divorced or separated parents. ( P  = .001). Conclusions FGIDs are common in children younger than 4 years of age. Functional constipation and infant colic were the most common FGIDs in infants (up to 12 months of age), and functional constipation and rumination were the most common FGIDs in children 13-48 months of age.
doi_str_mv 10.1016/j.jpeds.2016.08.095
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Study design We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants &amp; Toddlers. Results Parents of 1231 subjects completed the questionnaires; 48 children were excluded due to presence of organic diseases and being older than 48 months of age. Four hundred eighty children (40.5%) were diagnosed with at least 1 FGID according to the Rome III diagnostic criteria (49% female, median 12 months). Functional constipation was the most commonly diagnosed disorder in infants (up to 12 months of age) and children of ages 13-48 months (16.1% and 26.8%, respectively). Analysis revealed that the prevalence of FGID was significantly greater in children who were the only child in the family ( P  = .003), children who were first-born ( P  = .007), and children with divorced or separated parents. ( P  = .001). Conclusions FGIDs are common in children younger than 4 years of age. Functional constipation and infant colic were the most common FGIDs in infants (up to 12 months of age), and functional constipation and rumination were the most common FGIDs in children 13-48 months of age.</description><identifier>ISSN: 0022-3476</identifier><identifier>EISSN: 1097-6833</identifier><identifier>DOI: 10.1016/j.jpeds.2016.08.095</identifier><identifier>PMID: 27726867</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Child, Preschool ; children ; colic ; Colombia - epidemiology ; constipation ; Cross-Sectional Studies ; cyclic vomiting syndrome ; Female ; functional diarrhea ; functional dyschezia ; functional gastrointestinal disorders ; Gastrointestinal Diseases - epidemiology ; Humans ; Infant ; infants ; Male ; Pediatrics ; Prevalence ; regurgitation ; Rome III criteria ; rumination ; toddlers</subject><ispartof>The Journal of pediatrics, 2016-12, Vol.179, p.139-143.e1</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-18362d8f8dfa16b8e598275cab74e04908b419340f0ff8157184c1ded5ffc1fc3</citedby><cites>FETCH-LOGICAL-c414t-18362d8f8dfa16b8e598275cab74e04908b419340f0ff8157184c1ded5ffc1fc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022347616308782$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27726867$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chogle, Ashish, MD, MPH</creatorcontrib><creatorcontrib>Velasco-Benitez, Carlos A., MD</creatorcontrib><creatorcontrib>Koppen, Ilan J., MD</creatorcontrib><creatorcontrib>Moreno, Jairo E., MD</creatorcontrib><creatorcontrib>Ramírez Hernández, Carmen R., MD</creatorcontrib><creatorcontrib>Saps, Miguel, MD</creatorcontrib><title>A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children</title><title>The Journal of pediatrics</title><addtitle>J Pediatr</addtitle><description>Objective To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. Study design We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants &amp; Toddlers. Results Parents of 1231 subjects completed the questionnaires; 48 children were excluded due to presence of organic diseases and being older than 48 months of age. Four hundred eighty children (40.5%) were diagnosed with at least 1 FGID according to the Rome III diagnostic criteria (49% female, median 12 months). Functional constipation was the most commonly diagnosed disorder in infants (up to 12 months of age) and children of ages 13-48 months (16.1% and 26.8%, respectively). Analysis revealed that the prevalence of FGID was significantly greater in children who were the only child in the family ( P  = .003), children who were first-born ( P  = .007), and children with divorced or separated parents. ( P  = .001). Conclusions FGIDs are common in children younger than 4 years of age. Functional constipation and infant colic were the most common FGIDs in infants (up to 12 months of age), and functional constipation and rumination were the most common FGIDs in children 13-48 months of age.</description><subject>Child, Preschool</subject><subject>children</subject><subject>colic</subject><subject>Colombia - epidemiology</subject><subject>constipation</subject><subject>Cross-Sectional Studies</subject><subject>cyclic vomiting syndrome</subject><subject>Female</subject><subject>functional diarrhea</subject><subject>functional dyschezia</subject><subject>functional gastrointestinal disorders</subject><subject>Gastrointestinal Diseases - epidemiology</subject><subject>Humans</subject><subject>Infant</subject><subject>infants</subject><subject>Male</subject><subject>Pediatrics</subject><subject>Prevalence</subject><subject>regurgitation</subject><subject>Rome III criteria</subject><subject>rumination</subject><subject>toddlers</subject><issn>0022-3476</issn><issn>1097-6833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkUFv1DAQhS0EokvhFyAhH7kkjBMncQ4glaUtSJVAKhw4WV57vHXI2qmdIO2_x2ELBy6cRh69N8_zDSEvGZQMWPtmKIcJTSqr_ChBlNA3j8iGQd8Vrajrx2QDUFVFzbv2jDxLaQCAngM8JWdV11WtaLsN2V_QL2FaRjW74Iv3KqGht_NijjR4Ot8hvZycwYMLY9jnnqVXi9erVo30WqU5BudnTLNbGx9cCtFgTNR5-j0sfk-3d240Ef1z8sSqMeGLh3pOvl1dft1-LG4-X3_aXtwUmjM-F0zUbWWEFcYq1u4ENr2oukarXccReA9ix1lfc7BgrWBNxwTXzKBprNXM6vqcvD7NnWK4X_LH5MEljeOoPIYlyRzQcNYx1mRpfZLqGFKKaOUU3UHFo2QgV8JykL8Jy5WwBCEz4ex69RCw7A5o_nr-IM2CtycB5jV_OowyaYdeo3ER9SxNcP8JePePX4_OO63GH3jENIQlZtZ5E5kqCfJ2PfJ6Y9bWIDpR1b8A2ZCjZQ</recordid><startdate>20161201</startdate><enddate>20161201</enddate><creator>Chogle, Ashish, MD, MPH</creator><creator>Velasco-Benitez, Carlos A., MD</creator><creator>Koppen, Ilan J., MD</creator><creator>Moreno, Jairo E., MD</creator><creator>Ramírez Hernández, Carmen R., MD</creator><creator>Saps, Miguel, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20161201</creationdate><title>A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children</title><author>Chogle, Ashish, MD, MPH ; Velasco-Benitez, Carlos A., MD ; Koppen, Ilan J., MD ; Moreno, Jairo E., MD ; Ramírez Hernández, Carmen R., MD ; Saps, Miguel, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-18362d8f8dfa16b8e598275cab74e04908b419340f0ff8157184c1ded5ffc1fc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Child, Preschool</topic><topic>children</topic><topic>colic</topic><topic>Colombia - epidemiology</topic><topic>constipation</topic><topic>Cross-Sectional Studies</topic><topic>cyclic vomiting syndrome</topic><topic>Female</topic><topic>functional diarrhea</topic><topic>functional dyschezia</topic><topic>functional gastrointestinal disorders</topic><topic>Gastrointestinal Diseases - epidemiology</topic><topic>Humans</topic><topic>Infant</topic><topic>infants</topic><topic>Male</topic><topic>Pediatrics</topic><topic>Prevalence</topic><topic>regurgitation</topic><topic>Rome III criteria</topic><topic>rumination</topic><topic>toddlers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chogle, Ashish, MD, MPH</creatorcontrib><creatorcontrib>Velasco-Benitez, Carlos A., MD</creatorcontrib><creatorcontrib>Koppen, Ilan J., MD</creatorcontrib><creatorcontrib>Moreno, Jairo E., MD</creatorcontrib><creatorcontrib>Ramírez Hernández, Carmen R., MD</creatorcontrib><creatorcontrib>Saps, Miguel, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chogle, Ashish, MD, MPH</au><au>Velasco-Benitez, Carlos A., MD</au><au>Koppen, Ilan J., MD</au><au>Moreno, Jairo E., MD</au><au>Ramírez Hernández, Carmen R., MD</au><au>Saps, Miguel, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children</atitle><jtitle>The Journal of pediatrics</jtitle><addtitle>J Pediatr</addtitle><date>2016-12-01</date><risdate>2016</risdate><volume>179</volume><spage>139</spage><epage>143.e1</epage><pages>139-143.e1</pages><issn>0022-3476</issn><eissn>1097-6833</eissn><abstract>Objective To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. Study design We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants &amp; Toddlers. Results Parents of 1231 subjects completed the questionnaires; 48 children were excluded due to presence of organic diseases and being older than 48 months of age. Four hundred eighty children (40.5%) were diagnosed with at least 1 FGID according to the Rome III diagnostic criteria (49% female, median 12 months). Functional constipation was the most commonly diagnosed disorder in infants (up to 12 months of age) and children of ages 13-48 months (16.1% and 26.8%, respectively). Analysis revealed that the prevalence of FGID was significantly greater in children who were the only child in the family ( P  = .003), children who were first-born ( P  = .007), and children with divorced or separated parents. ( P  = .001). Conclusions FGIDs are common in children younger than 4 years of age. Functional constipation and infant colic were the most common FGIDs in infants (up to 12 months of age), and functional constipation and rumination were the most common FGIDs in children 13-48 months of age.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27726867</pmid><doi>10.1016/j.jpeds.2016.08.095</doi></addata></record>
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subjects Child, Preschool
children
colic
Colombia - epidemiology
constipation
Cross-Sectional Studies
cyclic vomiting syndrome
Female
functional diarrhea
functional dyschezia
functional gastrointestinal disorders
Gastrointestinal Diseases - epidemiology
Humans
Infant
infants
Male
Pediatrics
Prevalence
regurgitation
Rome III criteria
rumination
toddlers
title A Population-Based Study on the Epidemiology of Functional Gastrointestinal Disorders in Young Children
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