The impact of partial T cell depletion on overall transplant-related toxicity, graft function and survival after HLA-identical allogeneic bone marrow transplantation in standard risk adult patients with leukemia

In this single-center study, a consecutive cohort of 59 adult patients transplanted with HLA-identical bone marrow and receiving graft-versus-host disease (GVHD) prophylaxis with either standard cyclosporine/methotrexate (n = 33) or partial T cell depletion (E-rosetting) (TCD, n = 26 were analyzed)....

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2001-11, Vol.28 (10), p.917-922
Hauptverfasser:	SCHOTS, R, VAN RIET, I, BEN OTHMAN, T, TRULLEMANS, F, DE WAELE, M, VAN CAMP, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow transplantation Bone Marrow Transplantation - adverse effects Bone Marrow Transplantation - methods Bone Marrow Transplantation - mortality Bone marrow, stem cells transplantation. Graft versus host reaction Care and treatment Chronic myeloid leukemia Cohort Studies Comparative analysis Complications Cyclosporins Depletion Dosage and administration Female Graft Survival Graft versus host disease Graft vs Host Disease - prevention & control Graft-versus-host reaction Grafting Growth factors Health aspects Histocompatibility antigen HLA Humans Kinetics Leukemia Leukemia - complications Leukemia - mortality Leukemia - therapy Leukocytes (neutrophilic) Lymphocyte Count Lymphocyte Depletion Lymphocytes Lymphocytes T Male Medical sciences Methotrexate Middle Aged Myelodysplastic syndrome Myeloid leukemia Prophylaxis Recurrence Remission Stem cell transplantation Survival Survival Analysis T cells T-Lymphocytes - cytology Toxicity Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous Transplantation, Isogeneic
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