Anti-influenza activity of monoterpene-derived substituted hexahydro-2H-chromenes

[Display omitted] The antiviral activity of 4-hydroxy-hexahydro-2H-chromenes and 4-fluorine-hexahydro-2H-chromenes with an aromatic substituent, synthesized from monoterpene (−)-verbenone, was studied for the first time. Five of 11 (45 per cent) of 4-hydroxy-hexahydro-2H-chromene-type compounds have...

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Veröffentlicht in:	Bioorganic & medicinal chemistry 2016-11, Vol.24 (21), p.5158-5161
Hauptverfasser:	Patrusheva, Oksana S., Zarubaev, Vladimir V., Shtro, Anna A., Orshanskaya, Yana R., Boldyrev, Sergey A., Ilyina, Irina V., Kurbakova, Svetlana Yu, Korchagina, Dina V., Volcho, Konstantin P., Salakhutdinov, Nariman F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Antiviral Agents - chemical synthesis Antiviral Agents - chemistry Antiviral Agents - pharmacology Benzopyrans - chemistry Benzopyrans - pharmacology Chromene Dose-Response Relationship, Drug Humans Influenza Influenza A virus - drug effects Microbial Sensitivity Tests Molecular Structure Monoterpene Monoterpenes - chemical synthesis Monoterpenes - chemistry Monoterpenes - pharmacology Structure-Activity Relationship
Online-Zugang:	Volltext
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