THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY
Abstract Pregnancy represents a state of heightened oxidative stress and inflammation, and these processes are further increased in pregnancy complications. The quality of the maternal diet is directly associated with maternal health and wellbeing, pregnancy and fetal outcomes, as well as the risk o...
Gespeichert in:
| Veröffentlicht in: | Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2016-10, Vol.113, p.33-39 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 39 |
|---|---|
| container_issue | |
| container_start_page | 33 |
| container_title | Prostaglandins, leukotrienes and essential fatty acids |
| container_volume | 113 |
| creator | Leghi, G.E Muhlhausler, B.S |
| description | Abstract Pregnancy represents a state of heightened oxidative stress and inflammation, and these processes are further increased in pregnancy complications. The quality of the maternal diet is directly associated with maternal health and wellbeing, pregnancy and fetal outcomes, as well as the risk of pregnancy complications. Long chain polyunsaturated fatty acids (LCPUFAs) have significant potential to modify placental and fetal lipid environments and thereby modulate health outcomes. The omega-3 (n-3) LCPUFA in particular have been shown to exhibit both antioxidant and anti-inflammatory properties, and have potential therapeutic applications in reducing oxidative damage and inflammation during pregnancy. The purpose of this review is to provide an overview of our current understanding of the impact of maternal n-3 LCPUFA supplementation on oxidative stress and inflammation during pregnancy, with a particular focus on effects on the mother and the placenta. |
| doi_str_mv | 10.1016/j.plefa.2016.08.010 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1835400084</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0952327816300849</els_id><sourcerecordid>1835400084</sourcerecordid><originalsourceid>FETCH-LOGICAL-c414t-ed5cf420c7431c5d03e91b77d16bee44b560c7c09081d3f1ca18fa72c03202f73</originalsourceid><addsrcrecordid>eNqFkVFr2zAQx0VZWbNun2Aw9LgXuyfJjp2HDYwjpwZHMbFTtifhyDI4c-LUSgZ93Sef3HR96MtAIO7u_7_jfofQZwIuATK927nHTjeVS23gQugCgSs0IT6jDg0pe4cmMPOpw2gQ3qAPxuwAgBLivUc3NAgoAAsn6E95zzFPEh6XeJVg4TCcxfkmiXCxyfOML7koozJdCTy-H-ncBg8cF-WaFwWOxBynIsmi5fIiSgUeG-ZZFI_GZ4Et8bWIsjFbLCM836xTscD5mi9EJOKfH9F1U3VGf3r5b9Em4WV872SrRRpHmaM84p0cXfuq8SiowGNE-TUwPSPbIKjJdKu15239qa0pmEFIatYQVZGwqQKqgFGgTcBu0ddL3-PQP561Ocl9a5Tuuuqg-7ORJGS-ZxmFnpWyi1QNvTGDbuRxaPfV8CQJyBG-3Mln-HKELyGUFr51fXkZcN7udf3q-UfbCr5dBNqu-bvVgzSq1Qel63bQ6iTrvv3PgO9v_KprD62qul_6SZtdfx4OlqAk0lAJshjvP56fTNm41oz9BTuRn2E</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1835400084</pqid></control><display><type>article</type><title>THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Leghi, G.E ; Muhlhausler, B.S</creator><creatorcontrib>Leghi, G.E ; Muhlhausler, B.S</creatorcontrib><description>Abstract Pregnancy represents a state of heightened oxidative stress and inflammation, and these processes are further increased in pregnancy complications. The quality of the maternal diet is directly associated with maternal health and wellbeing, pregnancy and fetal outcomes, as well as the risk of pregnancy complications. Long chain polyunsaturated fatty acids (LCPUFAs) have significant potential to modify placental and fetal lipid environments and thereby modulate health outcomes. The omega-3 (n-3) LCPUFA in particular have been shown to exhibit both antioxidant and anti-inflammatory properties, and have potential therapeutic applications in reducing oxidative damage and inflammation during pregnancy. The purpose of this review is to provide an overview of our current understanding of the impact of maternal n-3 LCPUFA supplementation on oxidative stress and inflammation during pregnancy, with a particular focus on effects on the mother and the placenta.</description><identifier>ISSN: 0952-3278</identifier><identifier>EISSN: 1532-2823</identifier><identifier>DOI: 10.1016/j.plefa.2016.08.010</identifier><identifier>PMID: 27720038</identifier><language>eng</language><publisher>Scotland: Elsevier Ltd</publisher><subject>Advanced Basic Science ; Anti-Inflammatory Agents - administration & dosage ; Anti-Inflammatory Agents - pharmacology ; Dietary Supplements ; Endocrinology & Metabolism ; Fatty Acids, Omega-3 - administration & dosage ; Fatty Acids, Omega-3 - pharmacology ; Female ; Humans ; Inflammation ; Maternal Nutritional Physiological Phenomena ; Nutrition ; Omega-3 fatty acids ; Oxidative stress ; Oxidative Stress - drug effects ; Placenta ; Placenta - drug effects ; Placenta - immunology ; Plasma - drug effects ; Plasma - immunology ; Pregnancy</subject><ispartof>Prostaglandins, leukotrienes and essential fatty acids, 2016-10, Vol.113, p.33-39</ispartof><rights>2016</rights><rights>Copyright © 2016. Published by Elsevier Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-ed5cf420c7431c5d03e91b77d16bee44b560c7c09081d3f1ca18fa72c03202f73</citedby><cites>FETCH-LOGICAL-c414t-ed5cf420c7431c5d03e91b77d16bee44b560c7c09081d3f1ca18fa72c03202f73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.plefa.2016.08.010$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27720038$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leghi, G.E</creatorcontrib><creatorcontrib>Muhlhausler, B.S</creatorcontrib><title>THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY</title><title>Prostaglandins, leukotrienes and essential fatty acids</title><addtitle>Prostaglandins Leukot Essent Fatty Acids</addtitle><description>Abstract Pregnancy represents a state of heightened oxidative stress and inflammation, and these processes are further increased in pregnancy complications. The quality of the maternal diet is directly associated with maternal health and wellbeing, pregnancy and fetal outcomes, as well as the risk of pregnancy complications. Long chain polyunsaturated fatty acids (LCPUFAs) have significant potential to modify placental and fetal lipid environments and thereby modulate health outcomes. The omega-3 (n-3) LCPUFA in particular have been shown to exhibit both antioxidant and anti-inflammatory properties, and have potential therapeutic applications in reducing oxidative damage and inflammation during pregnancy. The purpose of this review is to provide an overview of our current understanding of the impact of maternal n-3 LCPUFA supplementation on oxidative stress and inflammation during pregnancy, with a particular focus on effects on the mother and the placenta.</description><subject>Advanced Basic Science</subject><subject>Anti-Inflammatory Agents - administration & dosage</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Dietary Supplements</subject><subject>Endocrinology & Metabolism</subject><subject>Fatty Acids, Omega-3 - administration & dosage</subject><subject>Fatty Acids, Omega-3 - pharmacology</subject><subject>Female</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Maternal Nutritional Physiological Phenomena</subject><subject>Nutrition</subject><subject>Omega-3 fatty acids</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - drug effects</subject><subject>Placenta</subject><subject>Placenta - drug effects</subject><subject>Placenta - immunology</subject><subject>Plasma - drug effects</subject><subject>Plasma - immunology</subject><subject>Pregnancy</subject><issn>0952-3278</issn><issn>1532-2823</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkVFr2zAQx0VZWbNun2Aw9LgXuyfJjp2HDYwjpwZHMbFTtifhyDI4c-LUSgZ93Sef3HR96MtAIO7u_7_jfofQZwIuATK927nHTjeVS23gQugCgSs0IT6jDg0pe4cmMPOpw2gQ3qAPxuwAgBLivUc3NAgoAAsn6E95zzFPEh6XeJVg4TCcxfkmiXCxyfOML7koozJdCTy-H-ncBg8cF-WaFwWOxBynIsmi5fIiSgUeG-ZZFI_GZ4Et8bWIsjFbLCM836xTscD5mi9EJOKfH9F1U3VGf3r5b9Em4WV872SrRRpHmaM84p0cXfuq8SiowGNE-TUwPSPbIKjJdKu15239qa0pmEFIatYQVZGwqQKqgFGgTcBu0ddL3-PQP561Ocl9a5Tuuuqg-7ORJGS-ZxmFnpWyi1QNvTGDbuRxaPfV8CQJyBG-3Mln-HKELyGUFr51fXkZcN7udf3q-UfbCr5dBNqu-bvVgzSq1Qel63bQ6iTrvv3PgO9v_KprD62qul_6SZtdfx4OlqAk0lAJshjvP56fTNm41oz9BTuRn2E</recordid><startdate>20161001</startdate><enddate>20161001</enddate><creator>Leghi, G.E</creator><creator>Muhlhausler, B.S</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20161001</creationdate><title>THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY</title><author>Leghi, G.E ; Muhlhausler, B.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-ed5cf420c7431c5d03e91b77d16bee44b560c7c09081d3f1ca18fa72c03202f73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Advanced Basic Science</topic><topic>Anti-Inflammatory Agents - administration & dosage</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Dietary Supplements</topic><topic>Endocrinology & Metabolism</topic><topic>Fatty Acids, Omega-3 - administration & dosage</topic><topic>Fatty Acids, Omega-3 - pharmacology</topic><topic>Female</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Maternal Nutritional Physiological Phenomena</topic><topic>Nutrition</topic><topic>Omega-3 fatty acids</topic><topic>Oxidative stress</topic><topic>Oxidative Stress - drug effects</topic><topic>Placenta</topic><topic>Placenta - drug effects</topic><topic>Placenta - immunology</topic><topic>Plasma - drug effects</topic><topic>Plasma - immunology</topic><topic>Pregnancy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Leghi, G.E</creatorcontrib><creatorcontrib>Muhlhausler, B.S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Prostaglandins, leukotrienes and essential fatty acids</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Leghi, G.E</au><au>Muhlhausler, B.S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY</atitle><jtitle>Prostaglandins, leukotrienes and essential fatty acids</jtitle><addtitle>Prostaglandins Leukot Essent Fatty Acids</addtitle><date>2016-10-01</date><risdate>2016</risdate><volume>113</volume><spage>33</spage><epage>39</epage><pages>33-39</pages><issn>0952-3278</issn><eissn>1532-2823</eissn><abstract>Abstract Pregnancy represents a state of heightened oxidative stress and inflammation, and these processes are further increased in pregnancy complications. The quality of the maternal diet is directly associated with maternal health and wellbeing, pregnancy and fetal outcomes, as well as the risk of pregnancy complications. Long chain polyunsaturated fatty acids (LCPUFAs) have significant potential to modify placental and fetal lipid environments and thereby modulate health outcomes. The omega-3 (n-3) LCPUFA in particular have been shown to exhibit both antioxidant and anti-inflammatory properties, and have potential therapeutic applications in reducing oxidative damage and inflammation during pregnancy. The purpose of this review is to provide an overview of our current understanding of the impact of maternal n-3 LCPUFA supplementation on oxidative stress and inflammation during pregnancy, with a particular focus on effects on the mother and the placenta.</abstract><cop>Scotland</cop><pub>Elsevier Ltd</pub><pmid>27720038</pmid><doi>10.1016/j.plefa.2016.08.010</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0952-3278 |
| ispartof | Prostaglandins, leukotrienes and essential fatty acids, 2016-10, Vol.113, p.33-39 |
| issn | 0952-3278 1532-2823 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1835400084 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Advanced Basic Science Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - pharmacology Dietary Supplements Endocrinology & Metabolism Fatty Acids, Omega-3 - administration & dosage Fatty Acids, Omega-3 - pharmacology Female Humans Inflammation Maternal Nutritional Physiological Phenomena Nutrition Omega-3 fatty acids Oxidative stress Oxidative Stress - drug effects Placenta Placenta - drug effects Placenta - immunology Plasma - drug effects Plasma - immunology Pregnancy |
| title | THE EFFECT OF N-3 LCPUFA SUPPLEMENTATION ON OXIDATIVE STRESS AND INFLAMMATION IN THE PLACENTA AND MATERNAL PLASMA DURING PREGNANCY |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T13%3A33%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=THE%20EFFECT%20OF%20N-3%20LCPUFA%20SUPPLEMENTATION%20ON%20OXIDATIVE%20STRESS%20AND%20INFLAMMATION%20IN%20THE%20PLACENTA%20AND%20MATERNAL%20PLASMA%20DURING%20PREGNANCY&rft.jtitle=Prostaglandins,%20leukotrienes%20and%20essential%20fatty%20acids&rft.au=Leghi,%20G.E&rft.date=2016-10-01&rft.volume=113&rft.spage=33&rft.epage=39&rft.pages=33-39&rft.issn=0952-3278&rft.eissn=1532-2823&rft_id=info:doi/10.1016/j.plefa.2016.08.010&rft_dat=%3Cproquest_cross%3E1835400084%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1835400084&rft_id=info:pmid/27720038&rft_els_id=S0952327816300849&rfr_iscdi=true |