Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators

[Display omitted] Adenosine monophosphate-activated protein kinase (AMPK), a serine/threonine heterotrimeric protein kinase, is a critical regulator of cellular and whole body energy homeostasis. There are twelve known AMPK isoforms that are differentially expressed in tissues and species. Dysregula...

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Veröffentlicht in:	Bioorganic & medicinal chemistry letters 2016-11, Vol.26 (21), p.5139-5148
Hauptverfasser:	Cameron, Kimberly O., Kurumbail, Ravi G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allostery AMP-Activated Protein Kinases - chemistry AMP-Activated Protein Kinases - metabolism AMPK Animals CBM CBS Crystallography Enzyme Activation Enzyme activators Enzyme Activators - pharmacology Humans Phosphorylation Protein Conformation
Online-Zugang:	Volltext
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