Virtual microscopy improves sharing of deceased donor kidneys
Abstract Background Donor kidney biopsies used for offer evaluation may lengthen cold ischemia time. Our organ procurement organization began processing wedge biopsies and having them read using virtual microscopy (VM), as opposed to its prior routine of processing/reading at local hospitals. We hyp...
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| Veröffentlicht in: | The American journal of surgery 2016-10, Vol.212 (4), p.592-595 |
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| creator | Osband, Adena J., M.D Fyfe, Billie, M.D Laskow, David A., M.D |
| description | Abstract Background Donor kidney biopsies used for offer evaluation may lengthen cold ischemia time. Our organ procurement organization began processing wedge biopsies and having them read using virtual microscopy (VM), as opposed to its prior routine of processing/reading at local hospitals. We hypothesized that VM would decrease time to biopsy results and kidney acceptance. Methods All donor kidneys biopsied over 1 year were compared with those biopsied during the previous year ( n = 43, 40). Results Time to biopsy result was shortened using VM (5:04 vs 6:30, P = .04), and especially for those cases with cross-clamp between 5 pm and 5 am (4:49 vs 8:12, P < .01). Time to local acceptance was also significantly improved using VM for both the entire group (7:01 vs 9:52, P < .01) and the overnight subset (7:25 vs 11:10, P < .01). Conclusions Use of VM decreased time to biopsy result, with the most prominent effects seen during the overnight hours, resulting in shortened time to local acceptance of organs. |
| doi_str_mv | 10.1016/j.amjsurg.2016.06.009 |
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Our organ procurement organization began processing wedge biopsies and having them read using virtual microscopy (VM), as opposed to its prior routine of processing/reading at local hospitals. We hypothesized that VM would decrease time to biopsy results and kidney acceptance. Methods All donor kidneys biopsied over 1 year were compared with those biopsied during the previous year ( n = 43, 40). Results Time to biopsy result was shortened using VM (5:04 vs 6:30, P = .04), and especially for those cases with cross-clamp between 5 pm and 5 am (4:49 vs 8:12, P < .01). Time to local acceptance was also significantly improved using VM for both the entire group (7:01 vs 9:52, P < .01) and the overnight subset (7:25 vs 11:10, P < .01). Conclusions Use of VM decreased time to biopsy result, with the most prominent effects seen during the overnight hours, resulting in shortened time to local acceptance of organs.</description><identifier>ISSN: 0002-9610</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/j.amjsurg.2016.06.009</identifier><identifier>PMID: 27530976</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Biopsy ; Cold ; Deceased donor ; Donor Selection - methods ; Female ; Health Services Accessibility ; Humans ; Information Dissemination ; Ischemia ; Kidney - pathology ; Kidney transplant ; Kidney Transplantation ; Kidneys ; Male ; Microscopy ; Microscopy - methods ; Middle Aged ; New Jersey ; Quality ; Surgery ; Telepathology ; Timing issues ; Tissue and Organ Procurement ; Tissue Donors - supply & distribution ; Transplants & implants</subject><ispartof>The American journal of surgery, 2016-10, Vol.212 (4), p.592-595</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Oct 01, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-a94e387dbb3fb57473f7962b9d2a567bf3bd7f6323412ce7e736ec3e131d63ca3</citedby><cites>FETCH-LOGICAL-c481t-a94e387dbb3fb57473f7962b9d2a567bf3bd7f6323412ce7e736ec3e131d63ca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1828267941?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27530976$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Osband, Adena J., M.D</creatorcontrib><creatorcontrib>Fyfe, Billie, M.D</creatorcontrib><creatorcontrib>Laskow, David A., M.D</creatorcontrib><title>Virtual microscopy improves sharing of deceased donor kidneys</title><title>The American journal of surgery</title><addtitle>Am J Surg</addtitle><description>Abstract Background Donor kidney biopsies used for offer evaluation may lengthen cold ischemia time. Our organ procurement organization began processing wedge biopsies and having them read using virtual microscopy (VM), as opposed to its prior routine of processing/reading at local hospitals. We hypothesized that VM would decrease time to biopsy results and kidney acceptance. Methods All donor kidneys biopsied over 1 year were compared with those biopsied during the previous year ( n = 43, 40). Results Time to biopsy result was shortened using VM (5:04 vs 6:30, P = .04), and especially for those cases with cross-clamp between 5 pm and 5 am (4:49 vs 8:12, P < .01). Time to local acceptance was also significantly improved using VM for both the entire group (7:01 vs 9:52, P < .01) and the overnight subset (7:25 vs 11:10, P < .01). Conclusions Use of VM decreased time to biopsy result, with the most prominent effects seen during the overnight hours, resulting in shortened time to local acceptance of organs.</description><subject>Biopsy</subject><subject>Cold</subject><subject>Deceased donor</subject><subject>Donor Selection - methods</subject><subject>Female</subject><subject>Health Services Accessibility</subject><subject>Humans</subject><subject>Information Dissemination</subject><subject>Ischemia</subject><subject>Kidney - pathology</subject><subject>Kidney transplant</subject><subject>Kidney Transplantation</subject><subject>Kidneys</subject><subject>Male</subject><subject>Microscopy</subject><subject>Microscopy - methods</subject><subject>Middle Aged</subject><subject>New Jersey</subject><subject>Quality</subject><subject>Surgery</subject><subject>Telepathology</subject><subject>Timing issues</subject><subject>Tissue and Organ Procurement</subject><subject>Tissue Donors - supply & distribution</subject><subject>Transplants & implants</subject><issn>0002-9610</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk1r3DAQhkVoSTZpf0KKoZdevJU0tmQd2lJCPgqBHvpxFbI0TuXY1lZaB_bfV2Y3KeTSwoAYePRK875DyDmja0aZeN-vzdinOd6teW7XNBdVR2TFGqlK1jTwgqwopbxUgtETcppSn1vGKjgmJ1zWQJUUK_Lhp4_b2QzF6G0MyYbNrvDjJoYHTEX6ZaKf7orQFQ4tmoSucGEKsbj3bsJdekVedmZI-PpwnpEfV5ffL27K26_XXy4-35a2ati2NKpCaKRrW-jaWlYSOqkEb5Xjphay7aB1shPAoWLcokQJAi0gA-YEWANn5N1eN3_s94xpq0efLA6DmTDMSbMGalCSCfgPlEvF6kapjL59hvZhjlMeZKEaLqSqWKbqPbX4kyJ2ehP9aOJOM6qXKHSvD1HoJQpNc9FF_c1BfW5HdE-3Hr3PwKc9gNm5B49RJ-txsuh8RLvVLvh_PvHxmYId_OStGe5xh-nvNDpxTfW3ZR-Wdcg-UahEBX8Ac-uwlg</recordid><startdate>20161001</startdate><enddate>20161001</enddate><creator>Osband, Adena J., M.D</creator><creator>Fyfe, Billie, M.D</creator><creator>Laskow, David A., M.D</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20161001</creationdate><title>Virtual microscopy improves sharing of deceased donor kidneys</title><author>Osband, Adena J., M.D ; Fyfe, Billie, M.D ; Laskow, David A., M.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c481t-a94e387dbb3fb57473f7962b9d2a567bf3bd7f6323412ce7e736ec3e131d63ca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Biopsy</topic><topic>Cold</topic><topic>Deceased donor</topic><topic>Donor Selection - methods</topic><topic>Female</topic><topic>Health Services Accessibility</topic><topic>Humans</topic><topic>Information Dissemination</topic><topic>Ischemia</topic><topic>Kidney - pathology</topic><topic>Kidney transplant</topic><topic>Kidney Transplantation</topic><topic>Kidneys</topic><topic>Male</topic><topic>Microscopy</topic><topic>Microscopy - methods</topic><topic>Middle Aged</topic><topic>New Jersey</topic><topic>Quality</topic><topic>Surgery</topic><topic>Telepathology</topic><topic>Timing issues</topic><topic>Tissue and Organ Procurement</topic><topic>Tissue Donors - supply & distribution</topic><topic>Transplants & implants</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Osband, Adena J., M.D</creatorcontrib><creatorcontrib>Fyfe, Billie, M.D</creatorcontrib><creatorcontrib>Laskow, David A., M.D</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Osband, Adena J., M.D</au><au>Fyfe, Billie, M.D</au><au>Laskow, David A., M.D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Virtual microscopy improves sharing of deceased donor kidneys</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>2016-10-01</date><risdate>2016</risdate><volume>212</volume><issue>4</issue><spage>592</spage><epage>595</epage><pages>592-595</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><abstract>Abstract Background Donor kidney biopsies used for offer evaluation may lengthen cold ischemia time. Our organ procurement organization began processing wedge biopsies and having them read using virtual microscopy (VM), as opposed to its prior routine of processing/reading at local hospitals. We hypothesized that VM would decrease time to biopsy results and kidney acceptance. Methods All donor kidneys biopsied over 1 year were compared with those biopsied during the previous year ( n = 43, 40). Results Time to biopsy result was shortened using VM (5:04 vs 6:30, P = .04), and especially for those cases with cross-clamp between 5 pm and 5 am (4:49 vs 8:12, P < .01). Time to local acceptance was also significantly improved using VM for both the entire group (7:01 vs 9:52, P < .01) and the overnight subset (7:25 vs 11:10, P < .01). Conclusions Use of VM decreased time to biopsy result, with the most prominent effects seen during the overnight hours, resulting in shortened time to local acceptance of organs.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27530976</pmid><doi>10.1016/j.amjsurg.2016.06.009</doi><tpages>4</tpages></addata></record> |
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| subjects | Biopsy Cold Deceased donor Donor Selection - methods Female Health Services Accessibility Humans Information Dissemination Ischemia Kidney - pathology Kidney transplant Kidney Transplantation Kidneys Male Microscopy Microscopy - methods Middle Aged New Jersey Quality Surgery Telepathology Timing issues Tissue and Organ Procurement Tissue Donors - supply & distribution Transplants & implants |
| title | Virtual microscopy improves sharing of deceased donor kidneys |
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