Standardization of the homogeneous mobility shift assay protocol for evaluation of anti-infliximab antibodies. Application of the method to Crohn’s disease patients treated with infliximab

[Display omitted] The availability of a quantitative method to measure anti-infliximab (IFX) antibodies (ATI) would facilitate the implementation of therapeutic drug monitoring in clinical decision-making. Our aim was to standardize the homogeneous mobility shift assay (HMSA) used in the measure of...

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Veröffentlicht in:	Biochemical pharmacology 2016-12, Vol.122, p.33-41
Hauptverfasser:	Hernández-Breijo, B., Chaparro, M., Cano-Martínez, D., Guerra, I., Iborra, M., Cabriada, J.L., Bujanda, L., Taxonera, C., García-Sánchez, V., Marín-Jiménez, I., Barreiro-de Acosta, M., Vera, I., Martín-Arranz, M.D., Mesonero, F., Sempere, L., Gomollón, F., Hinojosa, J., Gisbert, J.P., Guijarro, L.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-drug antibodies Antibodies - blood Crohn Disease - blood Crohn Disease - drug therapy Crohn’s disease Electrophoretic Mobility Shift Assay - methods HMSA Humans Infliximab Infliximab - therapeutic use Prospective Studies
Online-Zugang:	Volltext
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