Structure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymes

Flavin-dependent halogenase (Fl-Hal) enzymes have been shown to halogenate a range of synthetic as well as natural aromatic compounds. The exquisite regioselectively of Fl-Hal enzymes can provide halogenated building blocks which are inaccessible using standard halogenation chemistries. Consequently...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Organic & biomolecular chemistry 2016-10, Vol.14 (39), p.9354-9361
Hauptverfasser:	Menon, Binuraj R. K, Latham, Jonathan, Dunstan, Mark S, Brandenburger, Eileen, Klemstein, Ulrike, Leys, David, Karthikeyan, Chinnan, Greaney, Michael F, Shepherd, Sarah A, Micklefield, Jason
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis - enzymology Bacterial Proteins - chemistry Bacterial Proteins - metabolism Catalytic Domain Circular Dichroism Crystallography, X-Ray Enzyme Stability FMN Reductase - chemistry FMN Reductase - metabolism Kinetics Models, Molecular Oxidoreductases - chemistry Oxidoreductases - metabolism Streptomyces - enzymology Substrate Specificity Transition Temperature
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!