Characterization of the Cytochrome c Membrane-Binding Site Using Cardiolipin-Containing Bicelles with NMR

Cytochrome (cyt) c transports electrons from Complex III to Complex IV in mitochondria. Cyt c is ordinarily anchored to the mitochondrial membrane through interaction with cardiolipin (CL), however its release into the cytosol initiates apoptosis. The cyt c interaction site with CL‐containing bicell...

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Veröffentlicht in:	Angewandte Chemie International Edition 2016-11, Vol.55 (45), p.14019-14022
Hauptverfasser:	Kobayashi, Hisashi, Nagao, Satoshi, Hirota, Shun
Format:	Artikel
Sprache:	eng
Schlagworte:	bicelles cytochrome c membrane proteins protein-lipid interaction solution NMR
Online-Zugang:	Volltext
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