Who Should Undergo Chronic Total Occlusion Percutaneous Coronary Intervention?: The EXPLORation Continues
Given greater patient, lesion, and technical complexity, CTO PCI carries higher risk as compared with non-CTO PCI (4,14), including potentially life-threatening complications, such as donor vessel thrombosis and perforation. [...]CTO PCI may require prolonged fluoroscopy time and contrast medium adm...
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| Veröffentlicht in: | Journal of the American College of Cardiology 2016-10, Vol.68 (15), p.1633-1636 |
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| container_title | Journal of the American College of Cardiology |
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| creator | Brilakis, Emmanouil S. Abdullah, Shuaib M. Banerjee, Subhash |
| description | Given greater patient, lesion, and technical complexity, CTO PCI carries higher risk as compared with non-CTO PCI (4,14), including potentially life-threatening complications, such as donor vessel thrombosis and perforation. [...]CTO PCI may require prolonged fluoroscopy time and contrast medium administration, although with use of newer x-ray systems, contrast medium volume rather than radiation dose is becoming the more common limiting factor for CTO PCI success. Two randomized controlled clinical trials comparing CTO PCI with medical therapy are currently under way: the DECISION-CTO (Drug-Eluting Stent Implantation Versus Optimal Medical Treatment in Patients With Chronic Total Occlusion; NCT01078051) trial and the EURO-CTO (European Study on the Utilization of Revascularization Versus Optimal Medical Therapy for the Treatment of Chronic Total Coronary Occlusions; NCT01760083) trial. [...]the SHINE CTO (Sham-Controlled Intervention to Improve Quality of Life in CTOs; NCT02784418) trial is randomizing patients to CTO PCI or a sham procedure to determine whether CTO PCI improves patients' symptoms. |
| doi_str_mv | 10.1016/j.jacc.2016.07.748 |
| format | Article |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Acute coronary syndromes Angina pectoris Cardiology Cardiovascular disease chronic total occlusion Clinical trials Coronary vessels Electrocardiography Heart attacks Humans myocardial infarction Patients Percutaneous Coronary Intervention ST Elevation Myocardial Infarction ST-elevation Stents Studies Success |
| title | Who Should Undergo Chronic Total Occlusion Percutaneous Coronary Intervention?: The EXPLORation Continues |
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