Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck

Background & Aims Some patients develop multiple squamous cell carcinomas (SCCs) in the upper aerodigestive tract, attributed to field cancerization; alcohol consumption has been associated with this process. We examined the association between multiple areas of dysplastic squamous epithelium wi...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2016-11, Vol.151 (5), p.860-869.e7
Hauptverfasser:	Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Kaneko, Kazuhiro, Oda, Ichiro, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Yoshii, Takako, Konishi, Kazuo, Yamanouchi, Takenori, Tsuda, Takashi, Omori, Tai, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Amanuma, Yusuke, Ohashi, Shinya, Matsuda, Tomonari, Ishikawa, Hideki, Yokoyama, Akira, Muto, Manabu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Alcohol Abstinence Alcohol Drinking - adverse effects Carcinogenesis Carcinoma, Squamous Cell - diagnostic imaging Carcinoma, Squamous Cell - epidemiology Carcinoma, Squamous Cell - etiology Carcinoma, Squamous Cell - pathology Drinking Alcohol Esophageal Neoplasms - diagnostic imaging Esophageal Neoplasms - epidemiology Esophageal Neoplasms - etiology Esophageal Neoplasms - pathology Esophageal Squamous Cell Carcinoma Esophagoscopy Esophagus - diagnostic imaging Esophagus - pathology Female Gastroenterology and Hepatology Genetics Methods Head and Neck Neoplasms - diagnostic imaging Head and Neck Neoplasms - epidemiology Head and Neck Neoplasms - etiology Head and Neck Neoplasms - pathology Humans Incidence Kaplan-Meier Estimate Longitudinal Studies Male Middle Aged Neoplasm Grading Neoplasms, Multiple Primary - diagnostic imaging Neoplasms, Multiple Primary - epidemiology Neoplasms, Multiple Primary - etiology Neoplasms, Multiple Primary - pathology Neoplasms, Second Primary - diagnostic imaging Neoplasms, Second Primary - epidemiology Neoplasms, Second Primary - etiology Neoplasms, Second Primary - pathology Optical Imaging Proportional Hazards Models Prospective Studies Risk Factor Risk Factors Smoking Cessation
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