Genomic organization and modulation of gene expression of the TGF-β and FGF pathways in the allotetraploid frog Xenopus laevis

Inductive interactions mediated by the TGF-β and FGF–MAPK pathways are essential for specification of the germ layers and embryonic body axes during early vertebrate embryogenesis. TGF-β and FGF ligands signal through receptor Ser/Thr and Tyr kinases, respectively, and these signaling pathways cross...

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Veröffentlicht in:	Developmental biology 2017-06, Vol.426 (2), p.336-359
Hauptverfasser:	Suzuki, Atsushi, Yoshida, Hitoshi, van Heeringen, Simon J., Takebayashi-Suzuki, Kimiko, Veenstra, Gert Jan C., Taira, Masanori
Format:	Artikel
Sprache:	eng
Schlagworte:	allopolyploidy Allotetraploidy Amino Acid Sequence Animals Body Patterning - genetics Diploidy Embryo, Nonmammalian - metabolism embryogenesis Embryonic Induction - genetics Epigenesis, Genetic FGF Fibroblast Growth Factors - genetics Fibroblast Growth Factors - metabolism frogs gene expression gene expression regulation Gene Expression Regulation, Developmental Genetic Speciation genome Genomic structure Genomics Ligands MAP Kinase Signaling System - genetics Molecular Sequence Annotation nucleotide sequences phosphotransferases (kinases) receptors Receptors, Growth Factor - physiology signal transduction Signal Transduction - genetics Smad Proteins - metabolism Tetraploidy TGF-β transforming growth factor beta Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism Xenopus Xenopus - genetics Xenopus laevis Xenopus laevis - genetics Xenopus laevis - metabolism Xenopus Proteins - genetics Xenopus Proteins - metabolism Xenopus tropicalis
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