Evaluation of C1q Status and Titer of De Novo Donor‐Specific Antibodies as Predictors of Allograft Survival

De novo donor‐specific antibodies (dnDSAs) that develop after renal transplantation are independent predictors of allograft loss. However, it is unknown if dnDSA C1q status or titer at the time of first detection can independently predict allograft loss. In a consecutive cohort of 508 renal transpla...

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Veröffentlicht in:	American journal of transplantation 2017-03, Vol.17 (3), p.703-711
Hauptverfasser:	Wiebe, C., Gareau, A. J., Pochinco, D., Gibson, I. W., Ho, J., Birk, P. E., Blydt‐Hansen, T., Karpinski, M., Goldberg, A., Storsley, L., Rush, D. N., Nickerson, P. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alloantibody Allografts antibody biology clinical research/practice Complement C1q - immunology Female Follow-Up Studies Glomerular Filtration Rate Graft Rejection - etiology Graft Survival - immunology Humans immunobiology Isoantibodies - blood Isoantibodies - immunology kidney (allograft) function/dysfunction Kidney Failure, Chronic - surgery Kidney Function Tests Kidney Transplantation - adverse effects kidney transplantation/nephrology Male organ transplantation in general Prognosis rejection: antibody‐mediated (ABMR) rejection: subclinical Risk Factors Survival Rate Tissue Donors translational research/science Transplant Recipients Transplants & implants
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