Early detection of human glioma sphere xenografts in mouse brain using diffusion MRI at 14.1 T

Glioma models have provided important insights into human brain cancers. Among the investigative tools, MRI has allowed their characterization and diagnosis. In this study, we investigated whether diffusion MRI might be a useful technique for early detection and characterization of slow‐growing and...

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Veröffentlicht in:	NMR in biomedicine 2016-11, Vol.29 (11), p.1577-1589
Hauptverfasser:	Porcari, P., Hegi, M. E., Lei, H., Hamou, M-F., Vassallo, I., Capuani, S., Gruetter, R., Mlynarik, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADC Algorithms Animals Brain Neoplasms - diagnostic imaging Brain Neoplasms - pathology brain tumours Cell Line, Tumor Diffusion Magnetic Resonance Imaging - methods diffusion MRI Early Detection of Cancer - methods Female Glioma - diagnostic imaging Glioma - pathology human glioma xenografts Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods immunohistochemistry Mice Mice, Nude MRS Neoplasm Invasiveness Reproducibility of Results Sensitivity and Specificity Spheroids, Cellular - pathology
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