Effect of Maternal Stress Prior to Conception on Hippocampal BDNF Signaling in Rat Offspring

Environmental factors, especially stress, can remain pervasive effects across the lifespan. Traumatic experiences are risk factors for the behavioral and emotional disorders. Since brain-derived neurotrophic factor (BDNF) is the important regulator of neural survival, development, and its genetic an...

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Veröffentlicht in:	Molecular neurobiology 2017-10, Vol.54 (8), p.6436-6445
Hauptverfasser:	Niknazar, Somayeh, Nahavandi, Arezo, Peyvandi, Ali Asghar, Peyvandi, Hassan, Zare Mehrjerdi, Fatemeh, Karimi, Mohsen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal reproduction Animals Anxiety Anxiety - metabolism Biomedical and Life Sciences Biomedicine Brain Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Breeding Cell Biology Corticosterone Corticosterone - blood DNA Methylation Emotional behavior Environmental factors Enzyme-linked immunosorbent assay Epigenetics Female Group dynamics Hippocampus Hippocampus - metabolism Life span Male Maternal & child health Maternal Exposure Maze Learning - physiology Mental disorders Neurobiology Neurology Neurosciences Offspring Pregnancy Prenatal Exposure Delayed Effects - metabolism Protein-tyrosine kinase Protein-tyrosine kinase receptors Rats Rats, Wistar Receptor, trkB - metabolism Risk factors Risk taking Rodents Signal Transduction - physiology Stress Stress, Psychological - metabolism Swimming TrkB receptors Western blotting
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