Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial

IMPORTANCE: Despite suggestions of potential harm from unnecessary oxygen therapy, critically ill patients spend substantial periods in a hyperoxemic state. A strategy of controlled arterial oxygenation is thus rational but has not been validated in clinical practice. OBJECTIVE: To assess whether a...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2016-10, Vol.316 (15), p.1583-1589
Hauptverfasser:	Girardis, Massimo, Busani, Stefano, Damiani, Elisa, Donati, Abele, Rinaldi, Laura, Marudi, Andrea, Morelli, Andrea, Antonelli, Massimo, Singer, Mervyn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Clinical outcomes Critical Illness Cross Infection - epidemiology Early Termination of Clinical Trials Female Hospital Mortality Humans Hyperoxia - prevention & control Intensive care Intensive Care Units - statistics & numerical data Length of Stay Liver Failure - epidemiology Male Middle Aged Oxygen - blood Oxygen Inhalation Therapy - methods Oxygen therapy Partial Pressure Shock - epidemiology
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