Cell type- and region-specific enhancement of adult hippocampal neurogenesis by daidzein in middle-aged female mice

Adult hippocampal neurogenesis is associated with various brain functions, such as learning, memory, and emotion. Intriguingly, reduction in new cell production in the hippocampus in middle age may underlie some of the cognitive deficits. Among several factors that may affect adult hippocampal neuro...

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Veröffentlicht in:	Neuropharmacology 2016-12, Vol.111, p.92-106
Hauptverfasser:	Yamada, Jun, Hatabe, Jun, Tankyo, Kaori, Jinno, Shozo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult hippocampal neurogenesis Aging Animals Apoptosis - drug effects CA1 Region, Hippocampal - cytology CA1 Region, Hippocampal - drug effects CA1 Region, Hippocampal - physiology Cell Proliferation - drug effects Daidzein Dendritic Spines - drug effects Dentate Gyrus - cytology Dentate Gyrus - drug effects Dentate Gyrus - physiology Dorsoventral difference Female Hippocampus - cytology Hippocampus - drug effects Hippocampus - physiology Interblade difference Isoflavone Isoflavones - administration & dosage Mice Mice, Inbred C57BL Neurogenesis - drug effects Neurons - cytology Neurons - drug effects Neurons - physiology
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