A novel filtration system for point of care washing of cellular therapy products

The cell therapy industry would greatly benefit from a simple point of care solution to remove dimethylsulphoxide (DMSO) from small‐volume thawed cell suspensions before injection. A novel dead‐end filtration device has been designed and validated, which takes advantage of the higher density of thaw...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2017-11, Vol.11 (11), p.3157-3167
Hauptverfasser:	Tostoes, Rui, Dodgson, John R., Weil, Ben, Gerontas, Spyridon, Mason, Chris, Veraitch, Farlan
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone marrow cell delivery Cell Line cell manufacturing cell processing Cell suspensions Cell therapy cell washing Cell- and Tissue-Based Therapy - instrumentation Cell- and Tissue-Based Therapy - methods Circuit design Comparative analysis Cryopreservation Cryopreservation - methods Cryoprotective Agents - chemistry Dimethyl Sulfoxide - chemistry Fetuses Fibroblasts - cytology Fibroblasts - metabolism Filtration Filtration - instrumentation Filtration - methods Fluid dynamics Fluid flow Fluorescein Humans Impurities Isothiocyanate Lungs Mesenchyme Optimization point of care Point-of-Care Systems Recovery Regenerative medicine stem cell processing Stem cells Therapy Tissue engineering Washing
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