Cigarette smoking alters sialylation in the Fallopian tube of women, with implications for the pathogenesis of ectopic pregnancy

SUMMARY Sialylation creates a negative charge on the cell surface that can interfere with blastocyst implantation. For example, α2,6‐sialylation on terminal galactose, catalyzed by the sialyltransferase ST6GAL1, inhibits the binding of galectin‐1, a β‐galactoside‐binding lectin. We recently reported...

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