Fusion of foreign T‐cell epitopes and addition of TLR agonists enhance immunity against Neospora caninum profilin in cattle

Summary We demonstrated recently that immunization with recombinant Neospora caninum profilin (rNcPRO) induces limited protection and a regulatory T‐cell response in mice. The aim of this study was to evaluate the immune response elicited by rNcPRO in cattle and assess a strategy to enhance its immu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Parasite immunology 2016-11, Vol.38 (11), p.663-669
Hauptverfasser:	Mansilla, F. C., Quintana, M. E., Cardoso, N. P., Capozzo, A. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - administration & dosage Animals Antibodies, Protozoan - immunology B-Lymphocytes - immunology Cattle Cattle Diseases - immunology Coccidiosis - immunology Coccidiosis - veterinary Epitopes, T-Lymphocyte Female Immunoglobulin G Interferon-gamma - immunology Mice Neospora - physiology Neospora caninum profilin Profilins - analysis Profilins - genetics Protozoan Vaccines - administration & dosage Protozoan Vaccines - immunology Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Recombinant Proteins - metabolism recombinant vaccines T-Lymphocytes, Regulatory - immunology Toll-Like Receptors - agonists
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!