Irisin inhibition of growth hormone secretion in cultured tilapia pituitary cells

Irisin, the product of fibronectin type III domain-containing protein 5 (FNDC5) gene, is well-documented to be a regulator of energy metabolism. At present, not much is known about its biological function in non-mammalian species. In this study, a full-length tilapia FDNC5 was cloned and its tissue...

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Veröffentlicht in:	Molecular and cellular endocrinology 2017-01, Vol.439, p.395-406
Hauptverfasser:	Lian, Anji, Li, Xin, Jiang, Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Base Sequence Biological Assay Cells, Cultured Cloning, Molecular DNA, Complementary - genetics Fibronectins - chemistry Fibronectins - genetics Fibronectins - metabolism Fibronectins - pharmacology Gene Expression Profiling Gene Expression Regulation - drug effects Growth hormone Growth Hormone - genetics Growth Hormone - metabolism Growth Hormone - secretion Hepatocytes Humans Immune Sera - metabolism Irisin MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - genetics Pituitary cells Pituitary Gland - cytology Recombinant Proteins - pharmacology Sequence Alignment Tilapia Tilapia - genetics Tilapia - metabolism Uncoupling Protein 1 - metabolism
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