Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome

Are follicular fluid (FF) sphingosine-1-phosphate (S1P) levels in patients at risk of developing ovarian hyperstimulation syndrome (OHSS) altered and in part responsible for the high vascular permeability observed in these patients. FF S1P levels are lower in FF from patients at risk of OHSS and tre...

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Veröffentlicht in:	Molecular human reproduction 2016-12, Vol.22 (12), p.852
Hauptverfasser:	Scotti, L, Di Pietro, M, Pascuali, N, Irusta, G, I de Zúñiga, Gomez Peña, M, Pomilio, C, Saravia, F, Tesone, M, Abramovich, D, Parborell, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Capillary Permeability - drug effects Cell Line Endothelial Cells - drug effects Female Follicular Fluid - metabolism Humans Immunoblotting Lysophospholipids - pharmacology Lysophospholipids - therapeutic use Microscopy, Confocal Ovarian Hyperstimulation Syndrome - drug therapy Ovarian Hyperstimulation Syndrome - metabolism Ovary - drug effects Ovary - metabolism Sphingosine - analogs & derivatives Sphingosine - pharmacology Sphingosine - therapeutic use
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