Feasibility of Three-Dimensional Placement of Human Therapeutic Stem Cells Using the Intracerebral Microinjection Instrument

Objectives The ability to safely place viable intracerebral grafts of human‐derived therapeutic stem cells in three‐dimensional (3D) space was assessed in a porcine model of human stereotactic surgery using the Intracerebral Microinjection Instrument (IMI) compared to a conventional straight cannula...

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Veröffentlicht in:	Neuromodulation (Malden, Mass.) Mass.), 2016-10, Vol.19 (7), p.708-716
Hauptverfasser:	Glud, Andreas Nørgaard, Bjarkam, Carsten Reidies, Azimi, Nima, Johe, Karl, Sorensen, Jens Christian, Cunningham, Miles
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - diagnostic imaging Brain - metabolism Brain - pathology Brain Injuries, Traumatic - diagnostic imaging Brain Injuries, Traumatic - surgery Disease Models, Animal Embryonic Stem Cells - physiology Functional neurosurgery Glial Fibrillary Acidic Protein - metabolism Humans Imaging, Three-Dimensional Magnetic Resonance Imaging Microinjections - methods minimal invasive surgery Phosphopyruvate Hydratase - metabolism stem cell transplantation Stem Cell Transplantation - methods stereotaxy sus scrofa domesticus Swine Swine, Miniature
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