Discovering essential and infection-related genes

Transposon-based approaches are very powerful for identification of essential and infection-related genes in bacteria, particularly in the context of microbial genomics. We describe recent progress in several of these approaches, and their underlying principles. The essential gene test (EGT) is a tr...

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Veröffentlicht in:	Current Opinion in Microbiology 2001-10, Vol.4 (5), p.515-519
Hauptverfasser:	Lehoux, Dario E, Sanschagrin, François, Levesque, Roger C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - genetics Bacteria - pathogenicity Bacterial Infections - microbiology Biotechnology - methods DNA Transposable Elements - genetics Drug Industry - methods essential genes Genes, Bacterial Genes, Essential Humans infection-related genes Mutagenesis, Insertional - methods TnM trasposon mutagenesis virulence Virulence - genetics
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