Zika Getting on Your Nerves? The Association with the Guillain–Barré Syndrome

Parra and colleagues 1 report in the Journal the results of a prospective study of 68 Colombian patients who had a syndrome consistent with the Guillain–Barré syndrome, 66 of whom had previously had symptoms of Zika virus (ZIKV) infection. Major strengths of this study include the documentation of a temporal relationship between the Guillain–Barré syndrome and ZIKV infection (marked by a substantial increase in the incidence of the Guillain–Barré syndrome after the introduction of ZIKV, from 20 to 90 cases per month throughout Colombia), the criteria applied for the diagnosis of the Guillain–Barré syndrome, and the molecular and serologic flavivirus data . . .