Effect of Risedronate on the Risk of Hip Fracture in Elderly Women
Hip fractures cause substantial disability and are associated with a high rate of death among elderly women, 1 but there have been few studies of the effects of drug treatment on the risk of hip fracture. Observational studies suggest that estrogen may reduce the risk of hip fracture. 2 – 4 Alendron...
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| Veröffentlicht in: | The New England journal of medicine 2001-02, Vol.344 (5), p.333-340 |
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| container_title | The New England journal of medicine |
| container_volume | 344 |
| creator | McClung, Michael R Geusens, Piet Miller, Paul D Zippel, Hartmut Bensen, William G Roux, Christian Adami, Silvano Fogelman, Ignac Diamond, Terrence Eastell, Richard Meunier, Pierre J Wasnich, Richard D Greenwald, Maria Kaufman, Jean-Marc Chesnut, Charles H Reginster, Jean-Yves |
| description | Hip fractures cause substantial disability and are associated with a high rate of death among elderly women,
1
but there have been few studies of the effects of drug treatment on the risk of hip fracture. Observational studies suggest that estrogen may reduce the risk of hip fracture.
2
–
4
Alendronate reduced the risk of hip fracture in postmenopausal women with low bone mass at the femoral neck or with previous vertebral fractures, but not in women without those risk factors.
5
,
6
Numerous risk factors for hip fracture have been identified.
7
–
13
In general, these risk factors can be categorized as skeletal . . . |
| doi_str_mv | 10.1056/NEJM200102013440503 |
| format | Article |
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1
but there have been few studies of the effects of drug treatment on the risk of hip fracture. Observational studies suggest that estrogen may reduce the risk of hip fracture.
2
–
4
Alendronate reduced the risk of hip fracture in postmenopausal women with low bone mass at the femoral neck or with previous vertebral fractures, but not in women without those risk factors.
5
,
6
Numerous risk factors for hip fracture have been identified.
7
–
13
In general, these risk factors can be categorized as skeletal . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM200102013440503</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; bisphosphonates ; Bone density ; Clinical trials ; elderly ; Fractures ; hip ; Hip joint ; Injuries of the limb. Injuries of the spine ; Medical sciences ; Older people ; Osteoporosis ; risedronate ; Traumas. Diseases due to physical agents</subject><ispartof>The New England journal of medicine, 2001-02, Vol.344 (5), p.333-340</ispartof><rights>Copyright © 2001 Massachusetts Medical Society. All rights reserved.</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c592t-a44e4041a45470fbb8100d00d85dd312bbae366600fd21e85516c90fa0b02c703</citedby><cites>FETCH-LOGICAL-c592t-a44e4041a45470fbb8100d00d85dd312bbae366600fd21e85516c90fa0b02c703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM200102013440503$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223950828?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,777,781,2746,2747,26084,27905,27906,52363,54045,64364,64366,64368,72218</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=865815$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>McClung, Michael R</creatorcontrib><creatorcontrib>Geusens, Piet</creatorcontrib><creatorcontrib>Miller, Paul D</creatorcontrib><creatorcontrib>Zippel, Hartmut</creatorcontrib><creatorcontrib>Bensen, William G</creatorcontrib><creatorcontrib>Roux, Christian</creatorcontrib><creatorcontrib>Adami, Silvano</creatorcontrib><creatorcontrib>Fogelman, Ignac</creatorcontrib><creatorcontrib>Diamond, Terrence</creatorcontrib><creatorcontrib>Eastell, Richard</creatorcontrib><creatorcontrib>Meunier, Pierre J</creatorcontrib><creatorcontrib>Wasnich, Richard D</creatorcontrib><creatorcontrib>Greenwald, Maria</creatorcontrib><creatorcontrib>Kaufman, Jean-Marc</creatorcontrib><creatorcontrib>Chesnut, Charles H</creatorcontrib><creatorcontrib>Reginster, Jean-Yves</creatorcontrib><title>Effect of Risedronate on the Risk of Hip Fracture in Elderly Women</title><title>The New England journal of medicine</title><description>Hip fractures cause substantial disability and are associated with a high rate of death among elderly women,
1
but there have been few studies of the effects of drug treatment on the risk of hip fracture. Observational studies suggest that estrogen may reduce the risk of hip fracture.
2
–
4
Alendronate reduced the risk of hip fracture in postmenopausal women with low bone mass at the femoral neck or with previous vertebral fractures, but not in women without those risk factors.
5
,
6
Numerous risk factors for hip fracture have been identified.
7
–
13
In general, these risk factors can be categorized as skeletal . . .</description><subject>Biological and medical sciences</subject><subject>bisphosphonates</subject><subject>Bone density</subject><subject>Clinical trials</subject><subject>elderly</subject><subject>Fractures</subject><subject>hip</subject><subject>Hip joint</subject><subject>Injuries of the limb. Injuries of the spine</subject><subject>Medical sciences</subject><subject>Older people</subject><subject>Osteoporosis</subject><subject>risedronate</subject><subject>Traumas. 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Injuries of the spine</topic><topic>Medical sciences</topic><topic>Older people</topic><topic>Osteoporosis</topic><topic>risedronate</topic><topic>Traumas. 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1
but there have been few studies of the effects of drug treatment on the risk of hip fracture. Observational studies suggest that estrogen may reduce the risk of hip fracture.
2
–
4
Alendronate reduced the risk of hip fracture in postmenopausal women with low bone mass at the femoral neck or with previous vertebral fractures, but not in women without those risk factors.
5
,
6
Numerous risk factors for hip fracture have been identified.
7
–
13
In general, these risk factors can be categorized as skeletal . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM200102013440503</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | The New England journal of medicine, 2001-02, Vol.344 (5), p.333-340 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Biological and medical sciences bisphosphonates Bone density Clinical trials elderly Fractures hip Hip joint Injuries of the limb. Injuries of the spine Medical sciences Older people Osteoporosis risedronate Traumas. Diseases due to physical agents |
| title | Effect of Risedronate on the Risk of Hip Fracture in Elderly Women |
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