Characterization of DNA Adducts and Tetraols Derived from anti-Benzo[ghi]fluoranthane-3,4-dihydrodiol-5,5a-epoxide

A total of seven DNA adducts and two racemic tetraols derived from anti-benzo[ghi]fluoranthene-3,4-dihydrodiol-5,5a-epoxide (anti-B[ghi]FDE, 2) were characterized by analyses of UV, 1H NMR, CD, and MALDI mass spectra. The structure of 2 is the first example of a diolepoxide in which a fully fused cy...

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Veröffentlicht in:	Chemical research in toxicology 2002-02, Vol.15 (2), p.187-197
Hauptverfasser:	Chang, Hui-Fang, Huffer, Duane M, Chiarelli, M. Paul, Cho, Bongsup P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Cattle Chromatography, High Pressure Liquid diol epoxides DNA Adducts - analysis DNA Adducts - chemistry Epoxy Compounds - analysis Epoxy Compounds - chemistry Fluorenes - analysis Fluorenes - chemistry Isomerism Molecular Conformation
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