Tactile stimulation and neonatal isolation affect behavior and oxidative status linked to cocaine administration in young rats

•Early tactile stimulation (TS) reduced cocaine-place preference in young rats.•TS and neonatal isolation (10min – NI10) reduced anxiety-like behavior in rats.•TS exposure increased catalase activity in brain of cocaine-treated rats.•NI (60min – NI60) increased protein oxidation in brain of cocaine-...

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Veröffentlicht in:	Behavioural processes 2014-03, Vol.103, p.297-305
Hauptverfasser:	Antoniazzi, Caren T.D., Boufleur, Nardeli, Pase, Camila S., Kuhn, Fábio T., Dias, Verônica T., Segat, Hecson J., Roversi, Karine, Roversi, Katiane, Benvegnú, Dalila M., Bürger, Marilise E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal ethology Animals Animals, Newborn - physiology Antioxidants - metabolism Anxiety - psychology Anxiety-like behavior Ascorbic Acid - blood Ascorbic Acid - metabolism Behavior, Animal - drug effects Behavior, Animal - physiology Biological and medical sciences Brain Chemistry - physiology Catalase - metabolism Cocaine Cocaine-Related Disorders - psychology Conditioned place preference Conditioning, Operant - physiology Erythrocytes - metabolism Female Fundamental and applied biological sciences. Psychology General aspects Handling (Psychology) Oxidative status Oxidative Stress - physiology Physical Stimulation Pregnancy Protein Carbonylation - physiology Psychology. Psychoanalysis. Psychiatry Rats Rats, Wistar Social Isolation - psychology Tactile stimulation Thiobarbituric Acid Reactive Substances - metabolism
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