Do patients prefer mesh or anterior colporrhaphy for primary correction of anterior vaginal wall prolapse: a labelled discrete choice experiment

Objective We investigated patients’ preferences for anterior colporrhaphy or mesh surgery as surgical correction of anterior vaginal wall prolapse. Design Labelled discrete choice experiment. Setting Three Dutch teaching hospitals. Population Women with anterior vaginal wall prolapse Pelvic Organ Pr...

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Veröffentlicht in:BJOG : an international journal of obstetrics and gynaecology 2015-05, Vol.122 (6), p.873-880
Hauptverfasser: Notten, KJB, Essers, BA, Weemhoff, M, Rutten, AGH, Donners, JJAE, Gestel, I, Kruitwagen, RFPM, Roovers, JPWR, Dirksen, CD
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container_issue 6
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container_title BJOG : an international journal of obstetrics and gynaecology
container_volume 122
creator Notten, KJB
Essers, BA
Weemhoff, M
Rutten, AGH
Donners, JJAE
Gestel, I
Kruitwagen, RFPM
Roovers, JPWR
Dirksen, CD
description Objective We investigated patients’ preferences for anterior colporrhaphy or mesh surgery as surgical correction of anterior vaginal wall prolapse. Design Labelled discrete choice experiment. Setting Three Dutch teaching hospitals. Population Women with anterior vaginal wall prolapse Pelvic Organ Prolapse Quantification stage 2 or more, indicated for anterior colporrhaphy (n = 100). Methods Discrete choice experiments are an attribute‐based survey method for measuring preferences. In this experiment, women were asked to choose between two treatment scenarios, mesh surgery or anterior colporrhaphy. These surgical treatments differed in four treatment attributes: (i) recurrence rate, (ii) exposure rate, (iii) infection rate, (iv) dyspareunia. Data were analysed using a multinomial logit model. Main outcome measures Women's preferences for anterior colporrhaphy or mesh surgery for the repair of vaginal wall prolapse. Results All treatment attributes, i.e. recurrence, exposure, infection and dyspareunia, proved to be significant in the woman's decision to choose mesh surgery (P 
doi_str_mv 10.1111/1471-0528.12924
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Design Labelled discrete choice experiment. Setting Three Dutch teaching hospitals. Population Women with anterior vaginal wall prolapse Pelvic Organ Prolapse Quantification stage 2 or more, indicated for anterior colporrhaphy (n = 100). Methods Discrete choice experiments are an attribute‐based survey method for measuring preferences. In this experiment, women were asked to choose between two treatment scenarios, mesh surgery or anterior colporrhaphy. These surgical treatments differed in four treatment attributes: (i) recurrence rate, (ii) exposure rate, (iii) infection rate, (iv) dyspareunia. Data were analysed using a multinomial logit model. Main outcome measures Women's preferences for anterior colporrhaphy or mesh surgery for the repair of vaginal wall prolapse. Results All treatment attributes, i.e. recurrence, exposure, infection and dyspareunia, proved to be significant in the woman's decision to choose mesh surgery (P &lt; 0.001), while only two attributes out of three, recurrence and infection, were significant for anterior colporrhaphy (P &lt; 0.001). The relative importance data showed that with regards to the four statistically significant attributes for mesh, dyspareunia was the most important attribute, and of the two significant attributes for anterior colporrhaphy, the risk of infection. Based on the attributes and levels in our discrete choice experiment, anterior colporrhaphy was preferred in 74% as a primary correction of anterior vaginal wall prolapse, followed by a preference for mesh in 26% of all choices. Conclusion This study showed that next to the risk of recurrence, other aspects like risk of infection, dyspareunia and exposure play a role in the woman's preference for a surgical treatment. In addition, our results indicate that anterior colporrhaphy is preferred in the majority of the choices, followed by a preference for mesh surgery in a quarter of all choice sets. However, these results represent the average preference of a sample of women and cannot be taken as the preference of each individual. In the medical decision‐making context, information from the current study should be personalised to fit patient's unique circumstances. For patients to construct their own, individual preferences, they should be well informed about the existence and magnitude of the potential benefits and risks related to either anterior colporrhaphy or mesh surgery.</description><identifier>ISSN: 1470-0328</identifier><identifier>EISSN: 1471-0528</identifier><identifier>DOI: 10.1111/1471-0528.12924</identifier><identifier>PMID: 25041082</identifier><identifier>CODEN: BIOGFQ</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Anterior colporrhaphy ; anterior vaginal wall prolapse ; Choice Behavior ; discrete choice experiment ; Female ; Gynecologic Surgical Procedures - instrumentation ; Gynecologic Surgical Procedures - methods ; Health Care Surveys ; Humans ; Logistic Models ; Medical disorders ; mesh related complications ; mesh surgery ; Patient Preference - psychology ; Patient Preference - statistics &amp; numerical data ; Patients ; patients’ preferences ; Postoperative Complications ; Preferences ; Recurrence ; Risk ; Surgical Mesh ; Surgical techniques ; Urogenital system ; Uterine Prolapse - surgery ; Vagina - surgery</subject><ispartof>BJOG : an international journal of obstetrics and gynaecology, 2015-05, Vol.122 (6), p.873-880</ispartof><rights>2014 Royal College of Obstetricians and Gynaecologists</rights><rights>2014 Royal College of Obstetricians and Gynaecologists.</rights><rights>Copyright © 2015 Royal College of Obstetricians and Gynaecologists</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4784-fdfe04f87b690fc6efb3582666dbce6a5b3ad8fb8c9a066d57a8e72ae61fa2893</citedby><cites>FETCH-LOGICAL-c4784-fdfe04f87b690fc6efb3582666dbce6a5b3ad8fb8c9a066d57a8e72ae61fa2893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2F1471-0528.12924$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2F1471-0528.12924$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25041082$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Notten, KJB</creatorcontrib><creatorcontrib>Essers, BA</creatorcontrib><creatorcontrib>Weemhoff, M</creatorcontrib><creatorcontrib>Rutten, AGH</creatorcontrib><creatorcontrib>Donners, JJAE</creatorcontrib><creatorcontrib>Gestel, I</creatorcontrib><creatorcontrib>Kruitwagen, RFPM</creatorcontrib><creatorcontrib>Roovers, JPWR</creatorcontrib><creatorcontrib>Dirksen, CD</creatorcontrib><title>Do patients prefer mesh or anterior colporrhaphy for primary correction of anterior vaginal wall prolapse: a labelled discrete choice experiment</title><title>BJOG : an international journal of obstetrics and gynaecology</title><addtitle>BJOG</addtitle><description>Objective We investigated patients’ preferences for anterior colporrhaphy or mesh surgery as surgical correction of anterior vaginal wall prolapse. Design Labelled discrete choice experiment. Setting Three Dutch teaching hospitals. Population Women with anterior vaginal wall prolapse Pelvic Organ Prolapse Quantification stage 2 or more, indicated for anterior colporrhaphy (n = 100). Methods Discrete choice experiments are an attribute‐based survey method for measuring preferences. In this experiment, women were asked to choose between two treatment scenarios, mesh surgery or anterior colporrhaphy. These surgical treatments differed in four treatment attributes: (i) recurrence rate, (ii) exposure rate, (iii) infection rate, (iv) dyspareunia. Data were analysed using a multinomial logit model. Main outcome measures Women's preferences for anterior colporrhaphy or mesh surgery for the repair of vaginal wall prolapse. Results All treatment attributes, i.e. recurrence, exposure, infection and dyspareunia, proved to be significant in the woman's decision to choose mesh surgery (P &lt; 0.001), while only two attributes out of three, recurrence and infection, were significant for anterior colporrhaphy (P &lt; 0.001). The relative importance data showed that with regards to the four statistically significant attributes for mesh, dyspareunia was the most important attribute, and of the two significant attributes for anterior colporrhaphy, the risk of infection. Based on the attributes and levels in our discrete choice experiment, anterior colporrhaphy was preferred in 74% as a primary correction of anterior vaginal wall prolapse, followed by a preference for mesh in 26% of all choices. Conclusion This study showed that next to the risk of recurrence, other aspects like risk of infection, dyspareunia and exposure play a role in the woman's preference for a surgical treatment. In addition, our results indicate that anterior colporrhaphy is preferred in the majority of the choices, followed by a preference for mesh surgery in a quarter of all choice sets. However, these results represent the average preference of a sample of women and cannot be taken as the preference of each individual. In the medical decision‐making context, information from the current study should be personalised to fit patient's unique circumstances. 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Design Labelled discrete choice experiment. Setting Three Dutch teaching hospitals. Population Women with anterior vaginal wall prolapse Pelvic Organ Prolapse Quantification stage 2 or more, indicated for anterior colporrhaphy (n = 100). Methods Discrete choice experiments are an attribute‐based survey method for measuring preferences. In this experiment, women were asked to choose between two treatment scenarios, mesh surgery or anterior colporrhaphy. These surgical treatments differed in four treatment attributes: (i) recurrence rate, (ii) exposure rate, (iii) infection rate, (iv) dyspareunia. Data were analysed using a multinomial logit model. Main outcome measures Women's preferences for anterior colporrhaphy or mesh surgery for the repair of vaginal wall prolapse. Results All treatment attributes, i.e. recurrence, exposure, infection and dyspareunia, proved to be significant in the woman's decision to choose mesh surgery (P &lt; 0.001), while only two attributes out of three, recurrence and infection, were significant for anterior colporrhaphy (P &lt; 0.001). The relative importance data showed that with regards to the four statistically significant attributes for mesh, dyspareunia was the most important attribute, and of the two significant attributes for anterior colporrhaphy, the risk of infection. Based on the attributes and levels in our discrete choice experiment, anterior colporrhaphy was preferred in 74% as a primary correction of anterior vaginal wall prolapse, followed by a preference for mesh in 26% of all choices. Conclusion This study showed that next to the risk of recurrence, other aspects like risk of infection, dyspareunia and exposure play a role in the woman's preference for a surgical treatment. In addition, our results indicate that anterior colporrhaphy is preferred in the majority of the choices, followed by a preference for mesh surgery in a quarter of all choice sets. However, these results represent the average preference of a sample of women and cannot be taken as the preference of each individual. In the medical decision‐making context, information from the current study should be personalised to fit patient's unique circumstances. For patients to construct their own, individual preferences, they should be well informed about the existence and magnitude of the potential benefits and risks related to either anterior colporrhaphy or mesh surgery.</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>25041082</pmid><doi>10.1111/1471-0528.12924</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Anterior colporrhaphy
anterior vaginal wall prolapse
Choice Behavior
discrete choice experiment
Female
Gynecologic Surgical Procedures - instrumentation
Gynecologic Surgical Procedures - methods
Health Care Surveys
Humans
Logistic Models
Medical disorders
mesh related complications
mesh surgery
Patient Preference - psychology
Patient Preference - statistics & numerical data
Patients
patients’ preferences
Postoperative Complications
Preferences
Recurrence
Risk
Surgical Mesh
Surgical techniques
Urogenital system
Uterine Prolapse - surgery
Vagina - surgery
title Do patients prefer mesh or anterior colporrhaphy for primary correction of anterior vaginal wall prolapse: a labelled discrete choice experiment
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