Biomarker identification from next-generation sequencing data for pathogen bacteria characterization and surveillance

The purpose was to develop an analytical pipeline for specific gene analysis and biomarker discovery from next generation sequencing (NGS) data. As a test case, the gene reference sequences of 24 strains of 13 serotypes and NGS reads of 32 serovar Newport, 48 Montevideo and 115 Enteritidis outbreak...

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Veröffentlicht in:	Biomarkers in medicine 2015-11, Vol.9 (11), p.1253-1264
Hauptverfasser:	Zhao, Weizhong, Chen, James J, Foley, Steven, Wang, Yuping, Zhao, Shaohua, Basinger, John, Zou, Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Bacteria Bacterial Proteins - genetics Bioinformatics bioinformatics pipeline biomarker Biomarkers Biomarkers - metabolism Biotechnology Data analysis Epidemics gene gene diversity Genes Genetic diversity Genetics Genomes Genomics Health surveillance High-Throughput Nucleotide Sequencing Humans Identification Methods Next-generation sequencing next-generation sequencing analysis Pathogens Phylogenetics Phylogeny Public health Salmonella Salmonella enterica Salmonella enterica - genetics Salmonella enterica - isolation & purification Salmonella enterica - metabolism Serotypes Trees
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