Corynebacterium ulcerans, an emerging human pathogen
While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Cor...
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Veröffentlicht in: | Future microbiology 2016-09, Vol.11 (9), p.1191-1208 |
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creator | Hacker, Elena Antunes, Camila A Mattos-Guaraldi, Ana L Burkovski, Andreas Tauch, Andreas |
description | While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Corynebacterium diphtheria, while systemic infections are also increasingly reported. Little is known about factors that contribute to host colonization and virulence of this zoonotic pathogen. Research in this field has received new impetus by the publication of several C. ulcerans genome sequences in the past years. This review gives a comprehensive overview of the basic knowledge of C. ulcerans, as well as the recent advances made in the analysis of putative virulence factors. |
doi_str_mv | 10.2217/fmb-2016-0085 |
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In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Corynebacterium diphtheria, while systemic infections are also increasingly reported. Little is known about factors that contribute to host colonization and virulence of this zoonotic pathogen. Research in this field has received new impetus by the publication of several C. ulcerans genome sequences in the past years. This review gives a comprehensive overview of the basic knowledge of C. ulcerans, as well as the recent advances made in the analysis of putative virulence factors.</description><identifier>ISSN: 1746-0913</identifier><identifier>EISSN: 1746-0921</identifier><identifier>DOI: 10.2217/fmb-2016-0085</identifier><identifier>PMID: 27545005</identifier><language>eng</language><publisher>England: Future Medicine Ltd</publisher><subject>Animals ; Apoptosis ; Bacteria ; Bacterial Proteins - genetics ; Bacterial Proteins - metabolism ; Cattle ; Cattle Diseases - microbiology ; Colonization ; Corynebacterium ; Corynebacterium - genetics ; Corynebacterium - pathogenicity ; Corynebacterium - physiology ; Corynebacterium Infections - microbiology ; Corynebacterium Infections - veterinary ; Corynebacterium ulcerans ; Dairy products ; Diphtheria ; Genomes ; Gram-positive bacteria ; Humans ; Infections ; Pathogens ; Phylogenetics ; Taxonomy ; Virulence ; Virulence factors ; Virulence Factors - genetics ; Virulence Factors - metabolism</subject><ispartof>Future microbiology, 2016-09, Vol.11 (9), p.1191-1208</ispartof><rights>Copyright Future Medicine Ltd Sep 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c420t-f6db197f760a41b1013493b2a90d747daf1a90ee34d292dcba2c4b5c3f9ca84e3</citedby><cites>FETCH-LOGICAL-c420t-f6db197f760a41b1013493b2a90d747daf1a90ee34d292dcba2c4b5c3f9ca84e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27545005$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hacker, Elena</creatorcontrib><creatorcontrib>Antunes, Camila A</creatorcontrib><creatorcontrib>Mattos-Guaraldi, Ana L</creatorcontrib><creatorcontrib>Burkovski, Andreas</creatorcontrib><creatorcontrib>Tauch, Andreas</creatorcontrib><title>Corynebacterium ulcerans, an emerging human pathogen</title><title>Future microbiology</title><addtitle>Future Microbiol</addtitle><description>While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. 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subjects | Animals Apoptosis Bacteria Bacterial Proteins - genetics Bacterial Proteins - metabolism Cattle Cattle Diseases - microbiology Colonization Corynebacterium Corynebacterium - genetics Corynebacterium - pathogenicity Corynebacterium - physiology Corynebacterium Infections - microbiology Corynebacterium Infections - veterinary Corynebacterium ulcerans Dairy products Diphtheria Genomes Gram-positive bacteria Humans Infections Pathogens Phylogenetics Taxonomy Virulence Virulence factors Virulence Factors - genetics Virulence Factors - metabolism |
title | Corynebacterium ulcerans, an emerging human pathogen |
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