Corynebacterium ulcerans, an emerging human pathogen

While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Cor...

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Veröffentlicht in:Future microbiology 2016-09, Vol.11 (9), p.1191-1208
Hauptverfasser: Hacker, Elena, Antunes, Camila A, Mattos-Guaraldi, Ana L, Burkovski, Andreas, Tauch, Andreas
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container_end_page 1208
container_issue 9
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container_title Future microbiology
container_volume 11
creator Hacker, Elena
Antunes, Camila A
Mattos-Guaraldi, Ana L
Burkovski, Andreas
Tauch, Andreas
description While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Corynebacterium diphtheria, while systemic infections are also increasingly reported. Little is known about factors that contribute to host colonization and virulence of this zoonotic pathogen. Research in this field has received new impetus by the publication of several C. ulcerans genome sequences in the past years. This review gives a comprehensive overview of the basic knowledge of C. ulcerans, as well as the recent advances made in the analysis of putative virulence factors.
doi_str_mv 10.2217/fmb-2016-0085
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subjects Animals
Apoptosis
Bacteria
Bacterial Proteins - genetics
Bacterial Proteins - metabolism
Cattle
Cattle Diseases - microbiology
Colonization
Corynebacterium
Corynebacterium - genetics
Corynebacterium - pathogenicity
Corynebacterium - physiology
Corynebacterium Infections - microbiology
Corynebacterium Infections - veterinary
Corynebacterium ulcerans
Dairy products
Diphtheria
Genomes
Gram-positive bacteria
Humans
Infections
Pathogens
Phylogenetics
Taxonomy
Virulence
Virulence factors
Virulence Factors - genetics
Virulence Factors - metabolism
title Corynebacterium ulcerans, an emerging human pathogen
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