Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery
This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow‐up an...
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Veröffentlicht in: | The breast journal 2015-05, Vol.21 (3), p.268-275 |
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creator | Biazus, Jorge Villanova Falcão, Christiane Cardoso Parizotto, Angela Ceconello Stumpf, Camile Cesa Cavalheiro, José Antônio Crespo Schuh, Fernando Cericatto, Rodrigo Zucatto, Ângela Erguy Melo, Márcia Portela |
description | This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow‐up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast‐conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30–50% of the volume grafted. All patients received the literature‐based recommendations for breast cancer treatment with complementary radiotherapy. The follow‐up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI‐RADS 3, suggesting fat necrosis. The remaining patients were classified as BI‐RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small‐ and medium‐sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization. |
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We analyze the impact in relation to mammographic follow‐up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast‐conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30–50% of the volume grafted. All patients received the literature‐based recommendations for breast cancer treatment with complementary radiotherapy. The follow‐up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI‐RADS 3, suggesting fat necrosis. The remaining patients were classified as BI‐RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small‐ and medium‐sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization.</description><identifier>ISSN: 1075-122X</identifier><identifier>EISSN: 1524-4741</identifier><identifier>DOI: 10.1111/tbj.12397</identifier><identifier>PMID: 25783210</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adipose Tissue - transplantation ; Adult ; Aged ; autologous fat grafting ; breast cancer ; Breast Neoplasms - surgery ; breast reconstruction ; breast-conserving surgery ; Female ; Follow-Up Studies ; Humans ; Length of Stay ; lipofilling ; Mammaplasty - methods ; Mastectomy, Segmental - methods ; Middle Aged ; Patient Satisfaction ; Prospective Studies ; Transplantation, Autologous</subject><ispartof>The breast journal, 2015-05, Vol.21 (3), p.268-275</ispartof><rights>2015 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4317-9c4a7a175f76c5f1297e3885f074f548de0ffec162e9665b1667276e789197793</citedby><cites>FETCH-LOGICAL-c4317-9c4a7a175f76c5f1297e3885f074f548de0ffec162e9665b1667276e789197793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Ftbj.12397$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Ftbj.12397$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25783210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Biazus, Jorge Villanova</creatorcontrib><creatorcontrib>Falcão, Christiane Cardoso</creatorcontrib><creatorcontrib>Parizotto, Angela Ceconello</creatorcontrib><creatorcontrib>Stumpf, Camile Cesa</creatorcontrib><creatorcontrib>Cavalheiro, José Antônio Crespo</creatorcontrib><creatorcontrib>Schuh, Fernando</creatorcontrib><creatorcontrib>Cericatto, Rodrigo</creatorcontrib><creatorcontrib>Zucatto, Ângela Erguy</creatorcontrib><creatorcontrib>Melo, Márcia Portela</creatorcontrib><title>Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery</title><title>The breast journal</title><addtitle>Breast J</addtitle><description>This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow‐up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast‐conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30–50% of the volume grafted. All patients received the literature‐based recommendations for breast cancer treatment with complementary radiotherapy. The follow‐up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI‐RADS 3, suggesting fat necrosis. The remaining patients were classified as BI‐RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small‐ and medium‐sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization.</description><subject>Adipose Tissue - transplantation</subject><subject>Adult</subject><subject>Aged</subject><subject>autologous fat grafting</subject><subject>breast cancer</subject><subject>Breast Neoplasms - surgery</subject><subject>breast reconstruction</subject><subject>breast-conserving surgery</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Length of Stay</subject><subject>lipofilling</subject><subject>Mammaplasty - methods</subject><subject>Mastectomy, Segmental - methods</subject><subject>Middle Aged</subject><subject>Patient Satisfaction</subject><subject>Prospective Studies</subject><subject>Transplantation, Autologous</subject><issn>1075-122X</issn><issn>1524-4741</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtP3DAURi1UxKtd9A9UWbaLgO3YvvESRjw1PFSmaruyPOF6GpqJqe0wzL_HMMCuwptrXZ3vk30I-czoLstnL01vdxmvNKyRLSa5KAUI9iHfKciScf5rk2zHeEsp5ZqKDbLJJdQVZ3SL_D6dz_GmtQmL79j4PqYwNKn1fbFo059if0i-8zM_xMLZVEyC7aPDUBz5rvOLtp8VBwFtTOUoRzHcP22uhzDDsPxI1p3tIn56mTvkx9HhZHRSji-PT0f747IRFYNSN8KCZSAdqEY6xjVgVdfSURBOivoGqXPYMMVRKyWnTCngoBBqzTSArnbI11XvXfD_BozJzNvYYNfZHvO7Dcs_5ULUGt5HFUimpAKR0W8rtAk-xoDO3IV2bsPSMGqepJss3TxLz-yXl9phmmW-ka-WM7C3AhZth8v_N5nJwdlrZblKtDHhw1vChr9GQQXS_Lw4NvL8XNZX19SMq0dKvZoY</recordid><startdate>201505</startdate><enddate>201505</enddate><creator>Biazus, Jorge Villanova</creator><creator>Falcão, Christiane Cardoso</creator><creator>Parizotto, Angela Ceconello</creator><creator>Stumpf, Camile Cesa</creator><creator>Cavalheiro, José Antônio Crespo</creator><creator>Schuh, Fernando</creator><creator>Cericatto, Rodrigo</creator><creator>Zucatto, Ângela Erguy</creator><creator>Melo, Márcia Portela</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>201505</creationdate><title>Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery</title><author>Biazus, Jorge Villanova ; Falcão, Christiane Cardoso ; Parizotto, Angela Ceconello ; Stumpf, Camile Cesa ; Cavalheiro, José Antônio Crespo ; Schuh, Fernando ; Cericatto, Rodrigo ; Zucatto, Ângela Erguy ; Melo, Márcia Portela</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4317-9c4a7a175f76c5f1297e3885f074f548de0ffec162e9665b1667276e789197793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adipose Tissue - transplantation</topic><topic>Adult</topic><topic>Aged</topic><topic>autologous fat grafting</topic><topic>breast cancer</topic><topic>Breast Neoplasms - surgery</topic><topic>breast reconstruction</topic><topic>breast-conserving surgery</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Length of Stay</topic><topic>lipofilling</topic><topic>Mammaplasty - methods</topic><topic>Mastectomy, Segmental - methods</topic><topic>Middle Aged</topic><topic>Patient Satisfaction</topic><topic>Prospective Studies</topic><topic>Transplantation, Autologous</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Biazus, Jorge Villanova</creatorcontrib><creatorcontrib>Falcão, Christiane Cardoso</creatorcontrib><creatorcontrib>Parizotto, Angela Ceconello</creatorcontrib><creatorcontrib>Stumpf, Camile Cesa</creatorcontrib><creatorcontrib>Cavalheiro, José Antônio Crespo</creatorcontrib><creatorcontrib>Schuh, Fernando</creatorcontrib><creatorcontrib>Cericatto, Rodrigo</creatorcontrib><creatorcontrib>Zucatto, Ângela Erguy</creatorcontrib><creatorcontrib>Melo, Márcia Portela</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>The breast journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Biazus, Jorge Villanova</au><au>Falcão, Christiane Cardoso</au><au>Parizotto, Angela Ceconello</au><au>Stumpf, Camile Cesa</au><au>Cavalheiro, José Antônio Crespo</au><au>Schuh, Fernando</au><au>Cericatto, Rodrigo</au><au>Zucatto, Ângela Erguy</au><au>Melo, Márcia Portela</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery</atitle><jtitle>The breast journal</jtitle><addtitle>Breast J</addtitle><date>2015-05</date><risdate>2015</risdate><volume>21</volume><issue>3</issue><spage>268</spage><epage>275</epage><pages>268-275</pages><issn>1075-122X</issn><eissn>1524-4741</eissn><abstract>This study explores the technical viability of autologous fat grafting for immediate partial breast reconstruction following the primary conservative surgery for breast cancer; restoring volume, shape, and symmetry to the treated breast. We analyze the impact in relation to mammographic follow‐up and the subjective degree of satisfaction with esthetic results and although we didn't have any local failure during the observation period; we understand that is too early for any kind of conclusion. From June of 2010 to July of 2011, 20 patients were selected for breast‐conserving surgery (BCS) with partial breast reconstruction with autologous fat grafting performed during the same operation by the same medical team. The fat graft was injected in the subcutaneous and intraglandular breast tissue around the resected area. We performed an overcorrection, predicting a resorbing of about 30–50% of the volume grafted. All patients received the literature‐based recommendations for breast cancer treatment with complementary radiotherapy. The follow‐up period after the completion of radiotherapy ranged from 13 to 29 months. The average volume grafted was 121 cc and it was 2.1 times larger than the resected volume. The esthetic scores were considered very good or good in the majority of cases. Mammograms were taken every 6 months after radiotherapy and only one patient had a mammogram classified as BI‐RADS 3, suggesting fat necrosis. The remaining patients were classified as BI‐RADS 2. Immediate autologous fat grafting is a promising technique for partial breast reconstruction after BCS. It is associated with high patient and physician satisfaction. It is an alternative for reconstruction of small‐ and medium‐sized breasts. This technique has the advantage that enables the reconstruction of defects in areas difficult to repair, particularly in the upper inner quadrants. It also may reduce the need for major glandular or myocutaneous flaps mobilization.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25783210</pmid><doi>10.1111/tbj.12397</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adipose Tissue - transplantation Adult Aged autologous fat grafting breast cancer Breast Neoplasms - surgery breast reconstruction breast-conserving surgery Female Follow-Up Studies Humans Length of Stay lipofilling Mammaplasty - methods Mastectomy, Segmental - methods Middle Aged Patient Satisfaction Prospective Studies Transplantation, Autologous |
title | Immediate Reconstruction with Autologous fat Transfer Following Breast-Conserving Surgery |
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