Fusion of Legionella pneumophila outer membrane vesicles with eukaryotic membrane systems is a mechanism to deliver pathogen factors to host cell membranes

Summary The formation and release of outer membrane vesicles (OMVs) is a phenomenon observed in many bacteria, including Legionella pneumophila. During infection, this human pathogen primarily invades alveolar macrophages and replicates within a unique membrane‐bound compartment termed Legionella‐co...

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Veröffentlicht in:	Cellular microbiology 2015-05, Vol.17 (5), p.607-620
Hauptverfasser:	Jäger, Jens, Keese, Susanne, Roessle, Manfred, Steinert, Michael, Schromm, Andra B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysical Phenomena Cell Membrane - metabolism Cells, Cultured Endocytosis Epithelial Cells - metabolism Exosomes - chemistry Exosomes - metabolism Fluorescence Resonance Energy Transfer Host-Pathogen Interactions Humans Legionella pneumophila Legionella pneumophila - cytology Legionella pneumophila - physiology Macrophages - immunology Macrophages - metabolism Scattering, Small Angle Spectroscopy, Fourier Transform Infrared Temperature Tumor Necrosis Factor-alpha - secretion Virulence Factors - metabolism
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