Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)

An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny...

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Veröffentlicht in:	Aquaculture 2002-04, Vol.206 (3), p.151-164
Hauptverfasser:	Palti, Y, Shirak, A, Cnaani, A, Hulata, G, Avtalion, R.R, Ron, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal aquaculture Animal productions Animals Aquaculture Biological and medical sciences Classical genetics, quantitative genetics, hybrids Deleterious genes DNA markers fish culture Freshwater Fundamental and applied biological sciences. Psychology Genes Genetics of eukaryotes. Biological and molecular evolution Genomics Gynogenesis Oreochromis aureus Pisciculture Tilapia Vertebrata Vertebrate aquaculture
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Zusammenfassung:	An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion ( P
ISSN:	0044-8486 1873-5622
DOI:	10.1016/S0044-8486(01)00727-X