Integrin alpha 3 beta 1 (CD 49c/29) Is a Cellular Receptor for Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8) Entry into the Target Cells

Human herpesvirus-8 (HHV-8) is implicated in the pathogenesis of Kaposi's sarcoma. HHV-8 envelope glycoprotein B possesses the RGD motif known to interact with integrin molecules, and HHV-8 infectivity was inhibited by RGD peptides, antibodies against RGD-dependent alpha 3 and beta 1 integrins,...

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Veröffentlicht in:	Cell 2002-02, Vol.108 (3), p.407-419
Hauptverfasser:	Akula, S M, Pramod, N P, Wang, Fu-Zhang, Chandran, B
Format:	Artikel
Sprache:	eng
Schlagworte:	FAK protein glycoprotein B Human herpesvirus 8
Online-Zugang:	Volltext
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