Functional restoration of human immunodeficiency virus and Epstein-Barr virus-specific CD8 super(+) T cells during highly active antiretroviral therapy is associated with an increase in CD4 super(+) T cells

To investigate the effect of highly active antiretroviral therapy (HAART) on HIV- and Epstein-Barr virus (EBV)-specific CD8 super(+) T cells, total number and function of these cells was determined in 16 HIV-infected individuals using tetrameric HLA-peptide complexes and IFN- gamma ELISPOT assays af...

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Veröffentlicht in:European journal of immunology 2002-04, Vol.32 (4), p.1080-1089
Hauptverfasser: Kostense, S, Otto, SA, Knol, G J, Manting, E H, Nanlohy, N M, Jansen, C, Lange, JMA, van Oers, MHJ, Miedema, F, van Baarle, D
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Sprache:eng
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