On the Sequencing of the Human Genome

Two recent papers using different approaches reported draft sequences of the human genome. The international Human Genome Project (HGP) used the hierarchical shotgun approach, whereas Celera Genomics adopted the whole-genome shotgun (WGS) approach. Here, we analyze whether the latter paper provides...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2002-03, Vol.99 (6), p.3712-3716
Hauptverfasser:	Waterston, Robert H., Lander, Eric S., Sulston, John E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Sciences Chromosomes, Artificial, Bacterial - genetics Chromosomes, Human, Pair 22 - genetics Cloning, Molecular Computational Biology - methods Computer Simulation Datasets Genome, Human Genomes Genomics Genomics - methods Human genome Human Genome Project Humans Models, Genetic Physical Chromosome Mapping - methods Physical Chromosome Mapping - standards Reproducibility of Results Scaffolds Sequence Analysis, DNA - methods Sequence Tagged Sites Sequencing Shotguns Tessellations Tiling
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