Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure
Although exercise oscillatory ventilation has emerged as a potent independent risk factor for adverse prognosis in heart failure, it is not well known whether cardiac rehabilitation can improve oscillatory ventilation. In this study, we investigated the magnitude of oscillations in ventilation befor...
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| Veröffentlicht in: | Heart and vessels 2016-10, Vol.31 (10), p.1659-1668 |
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| creator | Yamauchi, Fumitake Adachi, Hitoshi Tomono, Jun-ichi Toyoda, Shigeru Iwamatsu, Koichi Sakuma, Masashi Nakajima, Toshiaki Oshima, Shigeru Inoue, Teruo |
| description | Although exercise oscillatory ventilation has emerged as a potent independent risk factor for adverse prognosis in heart failure, it is not well known whether cardiac rehabilitation can improve oscillatory ventilation. In this study, we investigated the magnitude of oscillations in ventilation before and after cardiac rehabilitation in chronic heart failure patients with exercise oscillatory ventilation. Cardiac rehabilitation (5-month program) was performed in 26 patients with chronic heart failure who showed an oscillatory ventilation pattern during cardiopulmonary exercise testing (CPX). After the 5-month rehabilitation program was completed, the patients again underwent CPX. To determine the magnitude of oscillations in ventilation, the amplitude and cycle length of the oscillations were calculated and compared with several other parameters, including biomarkers that have established prognostic value in heart failure. At baseline before cardiac rehabilitation, both oscillation amplitude (
R
= 0.625,
P
|
| doi_str_mv | 10.1007/s00380-015-0782-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1827932964</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1825220871</sourcerecordid><originalsourceid>FETCH-LOGICAL-c429t-aa04a03685636b1788b97cb0833e63d2ffda933cb2b33b87a750d52bc234dcb3</originalsourceid><addsrcrecordid>eNqNkU1P3DAQhi1UBFvgB3CpLPXCJcUfie0cEQLaCokLd2vsTFijbLK1Hbr8-3oVWlVIlXryxzzz2qOHkHPOvnDG9GViTBpWMd5UTBtR7Q7IiqtyEo2WH8iKtZxVRgp9TD6m9MwK2PL2iBwLpYySWqzIy03fo8906ilQD7EL4GnENbgwhAw5TCPdxukpwoaWLe4w-pCQTsmHYYA8xVf6gmMOw8KGkX6HLYxYmG25KqVEf4a8pmuEmGkPYZgjnpLDHoaEZ2_rCXm8vXm8_lrdP9x9u766r3wt2lwBsBqYVKZRUjmujXGt9o4ZKVHJTvR9B62U3gknpTMadMO6RjgvZN15J0_IxRJbRvgxY8p2E5LH8vERpzlZboRupWhV_T9oIwQzmhf08zv0eZrjWObYU3VtmkaLQvGF8nFKKWJvtzFsIL5azuxen1302WLF7vXZXen59JY8uw12fzp--yqAWIBUSuMTxr-e_mfqL1u4pqw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1824485572</pqid></control><display><type>article</type><title>Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Yamauchi, Fumitake ; Adachi, Hitoshi ; Tomono, Jun-ichi ; Toyoda, Shigeru ; Iwamatsu, Koichi ; Sakuma, Masashi ; Nakajima, Toshiaki ; Oshima, Shigeru ; Inoue, Teruo</creator><creatorcontrib>Yamauchi, Fumitake ; Adachi, Hitoshi ; Tomono, Jun-ichi ; Toyoda, Shigeru ; Iwamatsu, Koichi ; Sakuma, Masashi ; Nakajima, Toshiaki ; Oshima, Shigeru ; Inoue, Teruo</creatorcontrib><description><![CDATA[Although exercise oscillatory ventilation has emerged as a potent independent risk factor for adverse prognosis in heart failure, it is not well known whether cardiac rehabilitation can improve oscillatory ventilation. In this study, we investigated the magnitude of oscillations in ventilation before and after cardiac rehabilitation in chronic heart failure patients with exercise oscillatory ventilation. Cardiac rehabilitation (5-month program) was performed in 26 patients with chronic heart failure who showed an oscillatory ventilation pattern during cardiopulmonary exercise testing (CPX). After the 5-month rehabilitation program was completed, the patients again underwent CPX. To determine the magnitude of oscillations in ventilation, the amplitude and cycle length of the oscillations were calculated and compared with several other parameters, including biomarkers that have established prognostic value in heart failure. At baseline before cardiac rehabilitation, both oscillation amplitude (
R
= 0.625,
P
< 0.01) and cycle length (
R
= 0.469,
P
< 0.05) were positively correlated with the slope of minute ventilation vs. carbon dioxide production. Plasma BNP levels were positively correlated with amplitude (
R
= 0.615,
P
< 0.01) but not cycle length (
R
= 0.371). Cardiac rehabilitation decreased oscillation amplitude (
P
< 0.01) but failed to change cycle length. The change in amplitude was positively correlated with the change in BNP levels (
R
= 0.760,
P
< 0.01). Multiple regression analysis showed that only the change in amplitude was an independent predictor of the change in BNP levels (
R
= 0.717,
P
< 0.01). A 5-month cardiac rehabilitation program improves exercise oscillatory ventilation in chronic heart failure patients by reducing the oscillation amplitude. This effect is associated with a reduction of plasma BNP levels, potentially contributing to an improvement of heart failure.]]></description><identifier>ISSN: 0910-8327</identifier><identifier>EISSN: 1615-2573</identifier><identifier>DOI: 10.1007/s00380-015-0782-x</identifier><identifier>PMID: 26686372</identifier><identifier>CODEN: HEVEEO</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Aged ; Biomedical Engineering and Bioengineering ; Cardiac Rehabilitation - methods ; Cardiac Surgery ; Cardiology ; Echocardiography ; Exercise ; Exercise Test ; Exercise Tolerance ; Female ; Heart failure ; Heart Failure - therapy ; Hematologic Tests ; Humans ; Linear Models ; Male ; Medical prognosis ; Medical tests ; Medicine ; Medicine & Public Health ; Middle Aged ; Natriuretic Peptide, Brain - blood ; Original Article ; Prognosis ; Rehabilitation ; Respiration ; Risk Factors ; Stroke Volume ; Vascular Surgery</subject><ispartof>Heart and vessels, 2016-10, Vol.31 (10), p.1659-1668</ispartof><rights>Springer Japan 2015</rights><rights>Springer Japan 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c429t-aa04a03685636b1788b97cb0833e63d2ffda933cb2b33b87a750d52bc234dcb3</citedby><cites>FETCH-LOGICAL-c429t-aa04a03685636b1788b97cb0833e63d2ffda933cb2b33b87a750d52bc234dcb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00380-015-0782-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00380-015-0782-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,777,781,27905,27906,41469,42538,51300</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26686372$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yamauchi, Fumitake</creatorcontrib><creatorcontrib>Adachi, Hitoshi</creatorcontrib><creatorcontrib>Tomono, Jun-ichi</creatorcontrib><creatorcontrib>Toyoda, Shigeru</creatorcontrib><creatorcontrib>Iwamatsu, Koichi</creatorcontrib><creatorcontrib>Sakuma, Masashi</creatorcontrib><creatorcontrib>Nakajima, Toshiaki</creatorcontrib><creatorcontrib>Oshima, Shigeru</creatorcontrib><creatorcontrib>Inoue, Teruo</creatorcontrib><title>Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure</title><title>Heart and vessels</title><addtitle>Heart Vessels</addtitle><addtitle>Heart Vessels</addtitle><description><![CDATA[Although exercise oscillatory ventilation has emerged as a potent independent risk factor for adverse prognosis in heart failure, it is not well known whether cardiac rehabilitation can improve oscillatory ventilation. In this study, we investigated the magnitude of oscillations in ventilation before and after cardiac rehabilitation in chronic heart failure patients with exercise oscillatory ventilation. Cardiac rehabilitation (5-month program) was performed in 26 patients with chronic heart failure who showed an oscillatory ventilation pattern during cardiopulmonary exercise testing (CPX). After the 5-month rehabilitation program was completed, the patients again underwent CPX. To determine the magnitude of oscillations in ventilation, the amplitude and cycle length of the oscillations were calculated and compared with several other parameters, including biomarkers that have established prognostic value in heart failure. At baseline before cardiac rehabilitation, both oscillation amplitude (
R
= 0.625,
P
< 0.01) and cycle length (
R
= 0.469,
P
< 0.05) were positively correlated with the slope of minute ventilation vs. carbon dioxide production. Plasma BNP levels were positively correlated with amplitude (
R
= 0.615,
P
< 0.01) but not cycle length (
R
= 0.371). Cardiac rehabilitation decreased oscillation amplitude (
P
< 0.01) but failed to change cycle length. The change in amplitude was positively correlated with the change in BNP levels (
R
= 0.760,
P
< 0.01). Multiple regression analysis showed that only the change in amplitude was an independent predictor of the change in BNP levels (
R
= 0.717,
P
< 0.01). A 5-month cardiac rehabilitation program improves exercise oscillatory ventilation in chronic heart failure patients by reducing the oscillation amplitude. This effect is associated with a reduction of plasma BNP levels, potentially contributing to an improvement of heart failure.]]></description><subject>Aged</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Cardiac Rehabilitation - methods</subject><subject>Cardiac Surgery</subject><subject>Cardiology</subject><subject>Echocardiography</subject><subject>Exercise</subject><subject>Exercise Test</subject><subject>Exercise Tolerance</subject><subject>Female</subject><subject>Heart failure</subject><subject>Heart Failure - therapy</subject><subject>Hematologic Tests</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medical tests</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Natriuretic Peptide, Brain - blood</subject><subject>Original Article</subject><subject>Prognosis</subject><subject>Rehabilitation</subject><subject>Respiration</subject><subject>Risk Factors</subject><subject>Stroke Volume</subject><subject>Vascular Surgery</subject><issn>0910-8327</issn><issn>1615-2573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkU1P3DAQhi1UBFvgB3CpLPXCJcUfie0cEQLaCokLd2vsTFijbLK1Hbr8-3oVWlVIlXryxzzz2qOHkHPOvnDG9GViTBpWMd5UTBtR7Q7IiqtyEo2WH8iKtZxVRgp9TD6m9MwK2PL2iBwLpYySWqzIy03fo8906ilQD7EL4GnENbgwhAw5TCPdxukpwoaWLe4w-pCQTsmHYYA8xVf6gmMOw8KGkX6HLYxYmG25KqVEf4a8pmuEmGkPYZgjnpLDHoaEZ2_rCXm8vXm8_lrdP9x9u766r3wt2lwBsBqYVKZRUjmujXGt9o4ZKVHJTvR9B62U3gknpTMadMO6RjgvZN15J0_IxRJbRvgxY8p2E5LH8vERpzlZboRupWhV_T9oIwQzmhf08zv0eZrjWObYU3VtmkaLQvGF8nFKKWJvtzFsIL5azuxen1302WLF7vXZXen59JY8uw12fzp--yqAWIBUSuMTxr-e_mfqL1u4pqw</recordid><startdate>20161001</startdate><enddate>20161001</enddate><creator>Yamauchi, Fumitake</creator><creator>Adachi, Hitoshi</creator><creator>Tomono, Jun-ichi</creator><creator>Toyoda, Shigeru</creator><creator>Iwamatsu, Koichi</creator><creator>Sakuma, Masashi</creator><creator>Nakajima, Toshiaki</creator><creator>Oshima, Shigeru</creator><creator>Inoue, Teruo</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20161001</creationdate><title>Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure</title><author>Yamauchi, Fumitake ; Adachi, Hitoshi ; Tomono, Jun-ichi ; Toyoda, Shigeru ; Iwamatsu, Koichi ; Sakuma, Masashi ; Nakajima, Toshiaki ; Oshima, Shigeru ; Inoue, Teruo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c429t-aa04a03685636b1788b97cb0833e63d2ffda933cb2b33b87a750d52bc234dcb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Cardiac Rehabilitation - methods</topic><topic>Cardiac Surgery</topic><topic>Cardiology</topic><topic>Echocardiography</topic><topic>Exercise</topic><topic>Exercise Test</topic><topic>Exercise Tolerance</topic><topic>Female</topic><topic>Heart failure</topic><topic>Heart Failure - therapy</topic><topic>Hematologic Tests</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medical tests</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Natriuretic Peptide, Brain - blood</topic><topic>Original Article</topic><topic>Prognosis</topic><topic>Rehabilitation</topic><topic>Respiration</topic><topic>Risk Factors</topic><topic>Stroke Volume</topic><topic>Vascular Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yamauchi, Fumitake</creatorcontrib><creatorcontrib>Adachi, Hitoshi</creatorcontrib><creatorcontrib>Tomono, Jun-ichi</creatorcontrib><creatorcontrib>Toyoda, Shigeru</creatorcontrib><creatorcontrib>Iwamatsu, Koichi</creatorcontrib><creatorcontrib>Sakuma, Masashi</creatorcontrib><creatorcontrib>Nakajima, Toshiaki</creatorcontrib><creatorcontrib>Oshima, Shigeru</creatorcontrib><creatorcontrib>Inoue, Teruo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Heart and vessels</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yamauchi, Fumitake</au><au>Adachi, Hitoshi</au><au>Tomono, Jun-ichi</au><au>Toyoda, Shigeru</au><au>Iwamatsu, Koichi</au><au>Sakuma, Masashi</au><au>Nakajima, Toshiaki</au><au>Oshima, Shigeru</au><au>Inoue, Teruo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure</atitle><jtitle>Heart and vessels</jtitle><stitle>Heart Vessels</stitle><addtitle>Heart Vessels</addtitle><date>2016-10-01</date><risdate>2016</risdate><volume>31</volume><issue>10</issue><spage>1659</spage><epage>1668</epage><pages>1659-1668</pages><issn>0910-8327</issn><eissn>1615-2573</eissn><coden>HEVEEO</coden><abstract><![CDATA[Although exercise oscillatory ventilation has emerged as a potent independent risk factor for adverse prognosis in heart failure, it is not well known whether cardiac rehabilitation can improve oscillatory ventilation. In this study, we investigated the magnitude of oscillations in ventilation before and after cardiac rehabilitation in chronic heart failure patients with exercise oscillatory ventilation. Cardiac rehabilitation (5-month program) was performed in 26 patients with chronic heart failure who showed an oscillatory ventilation pattern during cardiopulmonary exercise testing (CPX). After the 5-month rehabilitation program was completed, the patients again underwent CPX. To determine the magnitude of oscillations in ventilation, the amplitude and cycle length of the oscillations were calculated and compared with several other parameters, including biomarkers that have established prognostic value in heart failure. At baseline before cardiac rehabilitation, both oscillation amplitude (
R
= 0.625,
P
< 0.01) and cycle length (
R
= 0.469,
P
< 0.05) were positively correlated with the slope of minute ventilation vs. carbon dioxide production. Plasma BNP levels were positively correlated with amplitude (
R
= 0.615,
P
< 0.01) but not cycle length (
R
= 0.371). Cardiac rehabilitation decreased oscillation amplitude (
P
< 0.01) but failed to change cycle length. The change in amplitude was positively correlated with the change in BNP levels (
R
= 0.760,
P
< 0.01). Multiple regression analysis showed that only the change in amplitude was an independent predictor of the change in BNP levels (
R
= 0.717,
P
< 0.01). A 5-month cardiac rehabilitation program improves exercise oscillatory ventilation in chronic heart failure patients by reducing the oscillation amplitude. This effect is associated with a reduction of plasma BNP levels, potentially contributing to an improvement of heart failure.]]></abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>26686372</pmid><doi>10.1007/s00380-015-0782-x</doi><tpages>10</tpages></addata></record> |
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| subjects | Aged Biomedical Engineering and Bioengineering Cardiac Rehabilitation - methods Cardiac Surgery Cardiology Echocardiography Exercise Exercise Test Exercise Tolerance Female Heart failure Heart Failure - therapy Hematologic Tests Humans Linear Models Male Medical prognosis Medical tests Medicine Medicine & Public Health Middle Aged Natriuretic Peptide, Brain - blood Original Article Prognosis Rehabilitation Respiration Risk Factors Stroke Volume Vascular Surgery |
| title | Effect of a cardiac rehabilitation program on exercise oscillatory ventilation in Japanese patients with heart failure |
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