Evaluation of the tannic acid inhibitory effect against the NorA efflux pump of Staphylococcus aureus

During the early periods of antibiotic usage, bacterial infections were considered tamed. However, widespread antibiotic use has promoted the emergence of antibiotic-resistant pathogens, including multidrug resistant strains. Active efflux is a mechanism for bacterial resistance to inhibitory substa...

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Veröffentlicht in:	Microbial pathogenesis 2016-08, Vol.97, p.9-13
Hauptverfasser:	Tintino, Saulo R., Oliveira-Tintino, Cícera D.M., Campina, Fábia F., Silva, Raimundo L.P., Costa, Maria do S., Menezes, Irwin R.A., Calixto-Júnior, João T., Siqueira-Junior, José P., Coutinho, Henrique D.M., Leal-Balbino, Tereza C., Balbino, Valdir Q.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibiotic resistance Bacterial Proteins - antagonists & inhibitors Efflux pumps Enzyme Inhibitors - pharmacology Ethidium - pharmacology Microbial Sensitivity Tests Multidrug Resistance-Associated Proteins - antagonists & inhibitors NorA Staphylococcus aureus Staphylococcus aureus - drug effects Tannic acid Tannins - pharmacology
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