Tumor necrosis factor-α and interleukin-6 gene polymorphism association with susceptibility to celiac disease in Italian patients

The aim of this research was to study polymorphisms in the genes encoding cytokines interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in patients with celiac disease (CD) antigens DQ2 (DQ2-positive) or DQ8 (DQ8-positive). We compared the results with healthy controls to determine whether...

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Veröffentlicht in:	Genetics and molecular research 2015-12, Vol.14 (4), p.16343-16352
Hauptverfasser:	de Albuquerque Maranhão, R M, Martins Esteves, F A, Crovella, S, Segat, L, Eleutério Souza, P R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Alleles Case-Control Studies Celiac Disease - epidemiology Celiac Disease - genetics Child Child, Preschool Female Gene Frequency Genetic Association Studies Genetic Predisposition to Disease Genotype HLA-DQ Antigens - genetics Humans Interleukin-6 - genetics Italy - epidemiology Male Middle Aged Polymorphism, Single Nucleotide Tumor Necrosis Factor-alpha - genetics Young Adult
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