Identification and molecular cloning of a heparosan synthase from Pasteurella multocida type D

Pasteurella multocida Type D, a causative agent of atrophic rhinitis in swine and pasteurellosis in other domestic animals, produces an extracellular polysaccharide capsule that is a putative virulence factor. It was reported previously that the capsule was removed by treating microbes with heparin...

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Veröffentlicht in:	The Journal of biological chemistry 2002-03, Vol.277 (9), p.7209-7213
Hauptverfasser:	DeAngelis, Paul L, White, Carissa L
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Chromatography, Gel Cloning, Molecular Disaccharides - chemistry Dose-Response Relationship, Drug Escherichia coli - enzymology Escherichia coli Proteins Glycosyltransferases - biosynthesis Glycosyltransferases - chemistry Glycosyltransferases - genetics Heparin - metabolism heparosan synthase Ligases - chemistry Ligases - genetics Molecular Sequence Data N-Acetylglucosaminyltransferases - chemistry Pasteurella multocida Pasteurella multocida - enzymology Peptides - chemistry Polymers - chemistry Protein Structure, Tertiary Recombinant Proteins - chemistry Recombinant Proteins - metabolism Sequence Homology, Amino Acid Time Factors
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