Chronic perfluorooctanesulphonic acid (PFOS) exposure produces estrogenic effects in zebrafish

Perfluorooctanesulphonic acid (PFOS) is a ubiquitous contaminant in the aquatic environment and our earlier studies demonstrated that chronic PFOS exposures lead to a female-biased sex ratio and decreased sperm quality in male zebrafish. The underlying mechanism for these reproductive effects is unk...

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Veröffentlicht in:	Environmental pollution (1987) 2016-11, Vol.218, p.702-708
Hauptverfasser:	Chen, Jiangfei, Wang, Xiaotong, Ge, Xiaoqing, Wang, Dingding, Wang, Ting, Zhang, Lingnan, Tanguay, Robert L., Simonich, Michael, Huang, Changjiang, Dong, Qiaoxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Alkanesulfonic Acids - administration & dosage Alkanesulfonic Acids - toxicity Animals Danio rerio Drug Administration Schedule Estradiol - metabolism Estrogenic effects Female Fluorocarbons - administration & dosage Fluorocarbons - toxicity Gonad Gonadal Steroid Hormones - metabolism Gonads - drug effects Humans Male PFOS Reproduction - drug effects Sex hormone Sex Ratio Testis - drug effects Water Pollutants, Chemical - metabolism Water Pollutants, Chemical - toxicity Zebrafish
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