Anti- and Pro-apoptotic Bcl2 Proteins Distribution and Metabolic Profile in Human Coronary Aorta Endothelial Cells Before and After HypPDT

Understanding apoptosis regulatory mechanisms in endothelial cells (ECs) has great importance for the development of novel therapy strategies for cancer and cardiovascular pathologies. An oxidative stress with the generation of reactive oxygen species (ROS) is a common mechanism causing ECs’ dysfunc...

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Veröffentlicht in:	Cell biochemistry and biophysics 2016-09, Vol.74 (3), p.435-447
Hauptverfasser:	Maslaakova, Maria, Balogova, Lucia, Miskovsky, Pavol, TkaAeova, Ruzena, Stroffekova, Katarina
Format:	Artikel
Sprache:	eng
Schlagworte:	Aorta - cytology Apoptosis Regulatory Proteins - metabolism Biochemistry Biological and Medical Physics Biomedical and Life Sciences Biophysics Biotechnology Cell Biology Cell Survival - drug effects Endothelial Cells - cytology Endothelial Cells - drug effects Endothelial Cells - metabolism Humans Immunohistochemistry Life Sciences Metabolome - drug effects Microscopy, Fluorescence Mitochondria - drug effects Mitochondria - metabolism Original Paper Oxidative stress Oxidative Stress - drug effects Perylene - analogs & derivatives Perylene - pharmacology Pharmacology/Toxicology Photosensitizing Agents - pharmacology Proto-Oncogene Proteins c-bcl-2 - metabolism Reactive Oxygen Species - metabolism
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