Morphological and behavioral characterization of adult mice deficient for SrGAP3

SrGAP3 belongs to the family of Rho GTPase proteins. These proteins are thought to play essential roles in development and in the plasticity of the nervous system. SrGAP3-deficient mice have recently been created and approximately 10 % of these mice developed a hydrocephalus and died shortly after b...

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Veröffentlicht in:	Cell and tissue research 2016-10, Vol.366 (1), p.1-11
Hauptverfasser:	Bertram, Jonathan, Koschützke, Leif, Pfannmöller, Jörg P., Esche, Jennifer, van Diepen, Laura, Kuss, Andreas W., Hartmann, Bianca, Bartsch, Dusan, Lotze, Martin, von Bohlen und Halbach, Oliver
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Animal behavior Animals Behavior, Animal Biomedical and Life Sciences Biomedicine Brain Brain research Dendrites - metabolism Dentate Gyrus - anatomy & histology Dentate Gyrus - metabolism Golgi Apparatus - metabolism GTPase-Activating Proteins - deficiency GTPase-Activating Proteins - metabolism Hippocampus - anatomy & histology Hippocampus - metabolism Human Genetics Mice Molecular Medicine Morphology Neurogenesis NMR Nuclear magnetic resonance Organ Size Proteomics Regular Article Task Performance and Analysis
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