Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort
Objective The incidence and outcome of first‐episode substance‐induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1‐year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first‐episode cohort. Method Data were from a large (n...
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| Veröffentlicht in: | Acta psychiatrica Scandinavica 2016-10, Vol.134 (4), p.321-328 |
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| container_title | Acta psychiatrica Scandinavica |
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| creator | Thompson, A. Marwaha, S. Winsper, C. Everard, L. Jones, P. B. Fowler, D. Amos, T. Freemantle, N. Singh, S. P. Marshall, M. Sharma, V. Birchwood, M. |
| description | Objective
The incidence and outcome of first‐episode substance‐induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1‐year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first‐episode cohort.
Method
Data were from a large (n = 1027) cohort of first‐episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months.
Results
There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group.
Conclusions
First‐episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients. |
| doi_str_mv | 10.1111/acps.12623 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1827906554</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4171883681</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4643-bd360655fe74a5e12ef2d5ec38d3839bba720f8b0e48c81d1bc2f7eb178d953c3</originalsourceid><addsrcrecordid>eNp90MtO3DAUBmALtYKBsukDVJa6qZBCfUliZ4midkClF3WKQN1Yjn0Cpkmc2olg3r6ezsCii3pjWf78H-tH6DUlpzSt99qM8ZSykvE9tKAlIRnJc_ECLQghNCsrcnOADmO8T8eCErmPDpjIRVURvkC3qzsfpmyC0GM_T8b3gH2L49zESQ8GMjfY2YDFY1ybOz85g62LPlgI2A1Y406HW8BXn3DrQpwwjOnWwo5HF7Hxmwmv0MtWdxGOd_sRuvr44Ud9nl1-XV7UZ5eZycucZ43lJSmLogWR6wIog5bZAgyXlkteNY0WjLSyIZBLI6mljWGtgIYKaauCG36E3m1zx-B_zxAn1btooOv0AH6Oikomqs2EPNG3_9B7P4ch_S4pWlYFkVQmdbJVJvgYA7RqDK7XYa0oUZv61aZ-9bf-hN_sIuemB_tMn_pOgG7Bg-tg_Z8odVZ_Wz2FZts3Lk7w-PxGh1-qFFwU6vrLUn1f_azZzeelqvkfa_Wf6w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1816950818</pqid></control><display><type>article</type><title>Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Thompson, A. ; Marwaha, S. ; Winsper, C. ; Everard, L. ; Jones, P. B. ; Fowler, D. ; Amos, T. ; Freemantle, N. ; Singh, S. P. ; Marshall, M. ; Sharma, V. ; Birchwood, M.</creator><creatorcontrib>Thompson, A. ; Marwaha, S. ; Winsper, C. ; Everard, L. ; Jones, P. B. ; Fowler, D. ; Amos, T. ; Freemantle, N. ; Singh, S. P. ; Marshall, M. ; Sharma, V. ; Birchwood, M.</creatorcontrib><description>Objective
The incidence and outcome of first‐episode substance‐induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1‐year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first‐episode cohort.
Method
Data were from a large (n = 1027) cohort of first‐episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months.
Results
There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group.
Conclusions
First‐episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients.</description><identifier>ISSN: 0001-690X</identifier><identifier>EISSN: 1600-0447</identifier><identifier>DOI: 10.1111/acps.12623</identifier><identifier>PMID: 27479903</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>Adolescent ; cohort study ; Depressive Disorder - epidemiology ; Depressive Disorder - etiology ; Early intervention ; Early Medical Intervention - statistics & numerical data ; Female ; first-episode psychosis ; Humans ; Incidence ; Male ; outcome ; Patient Admission - statistics & numerical data ; Prognosis ; Psychoses, Substance-Induced - diagnosis ; Psychoses, Substance-Induced - epidemiology ; Psychoses, Substance-Induced - psychology ; Psychosis ; Quality of Life ; substance-induced psychotic disorders ; United Kingdom - epidemiology ; Young Adult</subject><ispartof>Acta psychiatrica Scandinavica, 2016-10, Vol.134 (4), p.321-328</ispartof><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>2016 John Wiley & Sons A/S, Published by John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4643-bd360655fe74a5e12ef2d5ec38d3839bba720f8b0e48c81d1bc2f7eb178d953c3</citedby><cites>FETCH-LOGICAL-c4643-bd360655fe74a5e12ef2d5ec38d3839bba720f8b0e48c81d1bc2f7eb178d953c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Facps.12623$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Facps.12623$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27479903$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thompson, A.</creatorcontrib><creatorcontrib>Marwaha, S.</creatorcontrib><creatorcontrib>Winsper, C.</creatorcontrib><creatorcontrib>Everard, L.</creatorcontrib><creatorcontrib>Jones, P. B.</creatorcontrib><creatorcontrib>Fowler, D.</creatorcontrib><creatorcontrib>Amos, T.</creatorcontrib><creatorcontrib>Freemantle, N.</creatorcontrib><creatorcontrib>Singh, S. P.</creatorcontrib><creatorcontrib>Marshall, M.</creatorcontrib><creatorcontrib>Sharma, V.</creatorcontrib><creatorcontrib>Birchwood, M.</creatorcontrib><title>Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort</title><title>Acta psychiatrica Scandinavica</title><addtitle>Acta Psychiatr Scand</addtitle><description>Objective
The incidence and outcome of first‐episode substance‐induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1‐year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first‐episode cohort.
Method
Data were from a large (n = 1027) cohort of first‐episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months.
Results
There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group.
Conclusions
First‐episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients.</description><subject>Adolescent</subject><subject>cohort study</subject><subject>Depressive Disorder - epidemiology</subject><subject>Depressive Disorder - etiology</subject><subject>Early intervention</subject><subject>Early Medical Intervention - statistics & numerical data</subject><subject>Female</subject><subject>first-episode psychosis</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>outcome</subject><subject>Patient Admission - statistics & numerical data</subject><subject>Prognosis</subject><subject>Psychoses, Substance-Induced - diagnosis</subject><subject>Psychoses, Substance-Induced - epidemiology</subject><subject>Psychoses, Substance-Induced - psychology</subject><subject>Psychosis</subject><subject>Quality of Life</subject><subject>substance-induced psychotic disorders</subject><subject>United Kingdom - epidemiology</subject><subject>Young Adult</subject><issn>0001-690X</issn><issn>1600-0447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90MtO3DAUBmALtYKBsukDVJa6qZBCfUliZ4midkClF3WKQN1Yjn0Cpkmc2olg3r6ezsCii3pjWf78H-tH6DUlpzSt99qM8ZSykvE9tKAlIRnJc_ECLQghNCsrcnOADmO8T8eCErmPDpjIRVURvkC3qzsfpmyC0GM_T8b3gH2L49zESQ8GMjfY2YDFY1ybOz85g62LPlgI2A1Y406HW8BXn3DrQpwwjOnWwo5HF7Hxmwmv0MtWdxGOd_sRuvr44Ud9nl1-XV7UZ5eZycucZ43lJSmLogWR6wIog5bZAgyXlkteNY0WjLSyIZBLI6mljWGtgIYKaauCG36E3m1zx-B_zxAn1btooOv0AH6Oikomqs2EPNG3_9B7P4ch_S4pWlYFkVQmdbJVJvgYA7RqDK7XYa0oUZv61aZ-9bf-hN_sIuemB_tMn_pOgG7Bg-tg_Z8odVZ_Wz2FZts3Lk7w-PxGh1-qFFwU6vrLUn1f_azZzeelqvkfa_Wf6w</recordid><startdate>201610</startdate><enddate>201610</enddate><creator>Thompson, A.</creator><creator>Marwaha, S.</creator><creator>Winsper, C.</creator><creator>Everard, L.</creator><creator>Jones, P. B.</creator><creator>Fowler, D.</creator><creator>Amos, T.</creator><creator>Freemantle, N.</creator><creator>Singh, S. P.</creator><creator>Marshall, M.</creator><creator>Sharma, V.</creator><creator>Birchwood, M.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope></search><sort><creationdate>201610</creationdate><title>Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort</title><author>Thompson, A. ; Marwaha, S. ; Winsper, C. ; Everard, L. ; Jones, P. B. ; Fowler, D. ; Amos, T. ; Freemantle, N. ; Singh, S. P. ; Marshall, M. ; Sharma, V. ; Birchwood, M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4643-bd360655fe74a5e12ef2d5ec38d3839bba720f8b0e48c81d1bc2f7eb178d953c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>cohort study</topic><topic>Depressive Disorder - epidemiology</topic><topic>Depressive Disorder - etiology</topic><topic>Early intervention</topic><topic>Early Medical Intervention - statistics & numerical data</topic><topic>Female</topic><topic>first-episode psychosis</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>outcome</topic><topic>Patient Admission - statistics & numerical data</topic><topic>Prognosis</topic><topic>Psychoses, Substance-Induced - diagnosis</topic><topic>Psychoses, Substance-Induced - epidemiology</topic><topic>Psychoses, Substance-Induced - psychology</topic><topic>Psychosis</topic><topic>Quality of Life</topic><topic>substance-induced psychotic disorders</topic><topic>United Kingdom - epidemiology</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thompson, A.</creatorcontrib><creatorcontrib>Marwaha, S.</creatorcontrib><creatorcontrib>Winsper, C.</creatorcontrib><creatorcontrib>Everard, L.</creatorcontrib><creatorcontrib>Jones, P. B.</creatorcontrib><creatorcontrib>Fowler, D.</creatorcontrib><creatorcontrib>Amos, T.</creatorcontrib><creatorcontrib>Freemantle, N.</creatorcontrib><creatorcontrib>Singh, S. P.</creatorcontrib><creatorcontrib>Marshall, M.</creatorcontrib><creatorcontrib>Sharma, V.</creatorcontrib><creatorcontrib>Birchwood, M.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Acta psychiatrica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thompson, A.</au><au>Marwaha, S.</au><au>Winsper, C.</au><au>Everard, L.</au><au>Jones, P. B.</au><au>Fowler, D.</au><au>Amos, T.</au><au>Freemantle, N.</au><au>Singh, S. P.</au><au>Marshall, M.</au><au>Sharma, V.</au><au>Birchwood, M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort</atitle><jtitle>Acta psychiatrica Scandinavica</jtitle><addtitle>Acta Psychiatr Scand</addtitle><date>2016-10</date><risdate>2016</risdate><volume>134</volume><issue>4</issue><spage>321</spage><epage>328</epage><pages>321-328</pages><issn>0001-690X</issn><eissn>1600-0447</eissn><abstract>Objective
The incidence and outcome of first‐episode substance‐induced psychotic disorder (SIPD) are unclear. The study aimed to compare the 1‐year outcomes of those given a SIPD diagnosis by clinicians compared to other psychosis diagnoses in a first‐episode cohort.
Method
Data were from a large (n = 1027) cohort of first‐episode psychosis (FEP) patients admitted to early intervention services in the UK (National EDEN). Diagnosis, including that of SIPD, was made by treating psychiatrists at baseline using ICD10 criteria. Details on symptoms, functioning, quality of life, relapse and recovery were available at baseline and 12 months.
Results
There were 67 cases of SIPD (6.5% of the cohort). At baseline, SIPD patients were no different to other psychoses on symptoms, functioning and quality of life. At 12 months, there was no difference in SIPD and other psychoses on functioning, quality of life or relapse and recovery rates. Levels of psychotic and general symptomatology were similar but depressive symptoms were higher in the SIPD group.
Conclusions
First‐episode psychosis patients with a diagnosis of SIPD do not appear to have better outcomes than those with other primary psychotic diagnoses. The higher levels of depressive symptoms may be a specific marker in these patients.</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>27479903</pmid><doi>10.1111/acps.12623</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-690X |
| ispartof | Acta psychiatrica Scandinavica, 2016-10, Vol.134 (4), p.321-328 |
| issn | 0001-690X 1600-0447 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent cohort study Depressive Disorder - epidemiology Depressive Disorder - etiology Early intervention Early Medical Intervention - statistics & numerical data Female first-episode psychosis Humans Incidence Male outcome Patient Admission - statistics & numerical data Prognosis Psychoses, Substance-Induced - diagnosis Psychoses, Substance-Induced - epidemiology Psychoses, Substance-Induced - psychology Psychosis Quality of Life substance-induced psychotic disorders United Kingdom - epidemiology Young Adult |
| title | Short-term outcome of substance-induced psychotic disorder in a large UK first episode psychosis cohort |
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