Prenatal examination of the area and morphology of the atrioventricular valves using four-dimensional ultrasound in normal and abnormal hearts

Objective Our aim is to evaluate the feasibility to examine the morphology and area of the atrioventricular (AV) valves in normal fetuses and fetuses with cardiac defects using spatiotemporal image correlation (STIC). Methods Atrioventricular valves were analyzed longitudinally in STIC volumes of 74...

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Veröffentlicht in:Prenatal diagnosis 2015-08, Vol.35 (8), p.741-747
Hauptverfasser: Adriaanse, B. M. E., Uittenbogaard, L. B., Tromp, C. H. N., Schaefer, S. S., Heymans, M. W., van Vugt, J. M. G., Haak, M. C.
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Sprache:eng
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Zusammenfassung:Objective Our aim is to evaluate the feasibility to examine the morphology and area of the atrioventricular (AV) valves in normal fetuses and fetuses with cardiac defects using spatiotemporal image correlation (STIC). Methods Atrioventricular valves were analyzed longitudinally in STIC volumes of 74 normal fetuses between the 15th and 36th week of pregnancy. The valve area was measured in a rendered view in diastole, the number of valve leaflets in systole. Longitudinal data analysis was performed using linear mixed models. Fifty fetuses with cardiac defects were examined. Results Examination of 355 STIC volumes of normal fetuses showed in 82.5% sufficient quality. The tricuspid valve leaflets were seen in 200 (68.3%) volumes and the mitral valve leaflets in 219 (74.7%) volumes. The tricuspid valve showed in 61.1% a round, 29.0% rectangle, and 8.9% elliptical shape and the mitral valve in 60.1% round, 28.0% rectangle, and 10.9% elliptical. Regression analysis revealed a positive relationship of the valve area with gestational age (p 
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.4569