Intrahepatic NK cells function suppressed in advanced liver fibrosis

Background Although numerous epidemiological studies indicate that hepatitis B virus‐related liver fibrosis (HBV‐LF), particularly cirrhosis, represents the main risk factor for liver cancer development, the mechanisms determining the persistence of fibrosis and liver cancer pathogenesis are still p...

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Veröffentlicht in:	European journal of clinical investigation 2016-10, Vol.46 (10), p.864-872
Hauptverfasser:	Li, Xiaoyan, Zhang, Min, Liu, Jing, Huang, Zhanlian, Zhao, Qiyi, Huang, Yuehua, Li, Xu, Gao, Zhiliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Female HBV infection Hepatitis B virus Hepatitis C, Chronic - physiopathology Humans immune dysfunction Immunohistochemistry Interferon-gamma - biosynthesis Killer Cells, Natural - metabolism Killer Cells, Natural - physiology Killer Cells, Natural - virology Liver Cirrhosis - physiopathology Liver Cirrhosis - virology liver fibrosis Male Middle Aged Natural Cytotoxicity Triggering Receptor 1 - metabolism natural killer cells Perforin - biosynthesis
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