Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia

Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigate...

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Veröffentlicht in:Comprehensive psychiatry 2016-10, Vol.70, p.32-40
Hauptverfasser: Kontis, Dimitrios, Theochari, Eirini, Nikolakopoulou, Mary, Andreopoulou, Angeliki, Vassos, Dimitrios, Grigoriou, Vasileios, Vassilouli, Spyridoula, Giannakopoulou, Dimitra, Kouloumbi, Maria, Tsaltas, Eleftheria
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container_title Comprehensive psychiatry
container_volume 70
creator Kontis, Dimitrios
Theochari, Eirini
Nikolakopoulou, Mary
Andreopoulou, Angeliki
Vassos, Dimitrios
Grigoriou, Vasileios
Vassilouli, Spyridoula
Giannakopoulou, Dimitra
Kouloumbi, Maria
Tsaltas, Eleftheria
description Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p < 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.
doi_str_mv 10.1016/j.comppsych.2016.06.009
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We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p &lt; 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.</description><identifier>ISSN: 0010-440X</identifier><identifier>EISSN: 1532-8384</identifier><identifier>DOI: 10.1016/j.comppsych.2016.06.009</identifier><identifier>PMID: 27624421</identifier><identifier>CODEN: COPYAV</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Cognition ; Cognition &amp; reasoning ; Employment ; Female ; Hospitalization ; Humans ; Illnesses ; Male ; Memory ; Middle Aged ; Obsessive-Compulsive Disorder - complications ; Obsessive-Compulsive Disorder - psychology ; Psychiatry ; Psychopathology ; Psychotropic drugs ; Schizophrenia ; Schizophrenia - complications ; Schizophrenic Psychology ; Social Behavior ; Social research ; Studies ; Young Adult</subject><ispartof>Comprehensive psychiatry, 2016-10, Vol.70, p.32-40</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. 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Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p &lt; 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. 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We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p &lt; 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27624421</pmid><doi>10.1016/j.comppsych.2016.06.009</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Aged
Cognition
Cognition & reasoning
Employment
Female
Hospitalization
Humans
Illnesses
Male
Memory
Middle Aged
Obsessive-Compulsive Disorder - complications
Obsessive-Compulsive Disorder - psychology
Psychiatry
Psychopathology
Psychotropic drugs
Schizophrenia
Schizophrenia - complications
Schizophrenic Psychology
Social Behavior
Social research
Studies
Young Adult
title Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia
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