Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia
Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigate...
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creator | Kontis, Dimitrios Theochari, Eirini Nikolakopoulou, Mary Andreopoulou, Angeliki Vassos, Dimitrios Grigoriou, Vasileios Vassilouli, Spyridoula Giannakopoulou, Dimitra Kouloumbi, Maria Tsaltas, Eleftheria |
description | Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p < 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance. |
doi_str_mv | 10.1016/j.comppsych.2016.06.009 |
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We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p < 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.</description><identifier>ISSN: 0010-440X</identifier><identifier>EISSN: 1532-8384</identifier><identifier>DOI: 10.1016/j.comppsych.2016.06.009</identifier><identifier>PMID: 27624421</identifier><identifier>CODEN: COPYAV</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Cognition ; Cognition & reasoning ; Employment ; Female ; Hospitalization ; Humans ; Illnesses ; Male ; Memory ; Middle Aged ; Obsessive-Compulsive Disorder - complications ; Obsessive-Compulsive Disorder - psychology ; Psychiatry ; Psychopathology ; Psychotropic drugs ; Schizophrenia ; Schizophrenia - complications ; Schizophrenic Psychology ; Social Behavior ; Social research ; Studies ; Young Adult</subject><ispartof>Comprehensive psychiatry, 2016-10, Vol.70, p.32-40</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Oct 01, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c487t-43809dff477e56f0cdb2d9fcd002829f38f14f64cf34dedd3354ce05f532de343</citedby><cites>FETCH-LOGICAL-c487t-43809dff477e56f0cdb2d9fcd002829f38f14f64cf34dedd3354ce05f532de343</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0010440X16300918$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27624421$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kontis, Dimitrios</creatorcontrib><creatorcontrib>Theochari, Eirini</creatorcontrib><creatorcontrib>Nikolakopoulou, Mary</creatorcontrib><creatorcontrib>Andreopoulou, Angeliki</creatorcontrib><creatorcontrib>Vassos, Dimitrios</creatorcontrib><creatorcontrib>Grigoriou, Vasileios</creatorcontrib><creatorcontrib>Vassilouli, Spyridoula</creatorcontrib><creatorcontrib>Giannakopoulou, Dimitra</creatorcontrib><creatorcontrib>Kouloumbi, Maria</creatorcontrib><creatorcontrib>Tsaltas, Eleftheria</creatorcontrib><title>Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia</title><title>Comprehensive psychiatry</title><addtitle>Compr Psychiatry</addtitle><description>Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p < 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Cognition</subject><subject>Cognition & reasoning</subject><subject>Employment</subject><subject>Female</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Illnesses</subject><subject>Male</subject><subject>Memory</subject><subject>Middle Aged</subject><subject>Obsessive-Compulsive Disorder - complications</subject><subject>Obsessive-Compulsive Disorder - psychology</subject><subject>Psychiatry</subject><subject>Psychopathology</subject><subject>Psychotropic drugs</subject><subject>Schizophrenia</subject><subject>Schizophrenia - complications</subject><subject>Schizophrenic Psychology</subject><subject>Social Behavior</subject><subject>Social research</subject><subject>Studies</subject><subject>Young Adult</subject><issn>0010-440X</issn><issn>1532-8384</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk1v1DAQhi0EokvhL0AkLlyyjD-SOBekquJLqtQDIHGzsva46yWxg520Cr8ep1uK1FOlkW15nnmt8TuEvKGwpUDr94etDsM4pkXvtyxfbCEHtE_IhlaclZJL8ZRsACiUQsDPE_IipQMASCnFc3LCmpoJweiGjJe7hCm5ayxWxbm_PaZlGKcwpKKLWHQpBe26CU1x46Z9scNpwljY2evJBe_8VeG8wRHz4qd-KYLNWlferdmcKpLeuz9h3Ef0rntJntmuT_jqbj8lPz59_H7-pby4_Pz1_Oyi1EI2Uym4hNZYK5oGq9qCNjtmWqsNAJOstVxaKmwttOXCoDGcV0IjVDa3b5ALfkreHXXHGH7PmCY1uKSx7zuPYU6KStbItpJQPwKlbQtV1ayqbx-ghzBHnxvJVF1zoOyWao6UjiGliFaN0Q1dXBQFtfqnDureP7X6pyAHtLny9Z3-vBvQ3Nf9MywDZ0cA899dO4wqaYdeo3ER9aRMcI945MMDDd0773TX_8IF0_-OVGIK1Ld1jNYpork_aKnkfwEOFcfb</recordid><startdate>20161001</startdate><enddate>20161001</enddate><creator>Kontis, Dimitrios</creator><creator>Theochari, Eirini</creator><creator>Nikolakopoulou, Mary</creator><creator>Andreopoulou, Angeliki</creator><creator>Vassos, Dimitrios</creator><creator>Grigoriou, Vasileios</creator><creator>Vassilouli, Spyridoula</creator><creator>Giannakopoulou, Dimitra</creator><creator>Kouloumbi, Maria</creator><creator>Tsaltas, Eleftheria</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20161001</creationdate><title>Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia</title><author>Kontis, Dimitrios ; Theochari, Eirini ; Nikolakopoulou, Mary ; Andreopoulou, Angeliki ; Vassos, Dimitrios ; Grigoriou, Vasileios ; Vassilouli, Spyridoula ; Giannakopoulou, Dimitra ; Kouloumbi, Maria ; Tsaltas, Eleftheria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c487t-43809dff477e56f0cdb2d9fcd002829f38f14f64cf34dedd3354ce05f532de343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Cognition</topic><topic>Cognition & reasoning</topic><topic>Employment</topic><topic>Female</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Illnesses</topic><topic>Male</topic><topic>Memory</topic><topic>Middle Aged</topic><topic>Obsessive-Compulsive Disorder - complications</topic><topic>Obsessive-Compulsive Disorder - psychology</topic><topic>Psychiatry</topic><topic>Psychopathology</topic><topic>Psychotropic drugs</topic><topic>Schizophrenia</topic><topic>Schizophrenia - complications</topic><topic>Schizophrenic Psychology</topic><topic>Social Behavior</topic><topic>Social research</topic><topic>Studies</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kontis, Dimitrios</creatorcontrib><creatorcontrib>Theochari, Eirini</creatorcontrib><creatorcontrib>Nikolakopoulou, Mary</creatorcontrib><creatorcontrib>Andreopoulou, Angeliki</creatorcontrib><creatorcontrib>Vassos, Dimitrios</creatorcontrib><creatorcontrib>Grigoriou, Vasileios</creatorcontrib><creatorcontrib>Vassilouli, Spyridoula</creatorcontrib><creatorcontrib>Giannakopoulou, Dimitra</creatorcontrib><creatorcontrib>Kouloumbi, Maria</creatorcontrib><creatorcontrib>Tsaltas, Eleftheria</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Comprehensive psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kontis, Dimitrios</au><au>Theochari, Eirini</au><au>Nikolakopoulou, Mary</au><au>Andreopoulou, Angeliki</au><au>Vassos, Dimitrios</au><au>Grigoriou, Vasileios</au><au>Vassilouli, Spyridoula</au><au>Giannakopoulou, Dimitra</au><au>Kouloumbi, Maria</au><au>Tsaltas, Eleftheria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia</atitle><jtitle>Comprehensive psychiatry</jtitle><addtitle>Compr Psychiatry</addtitle><date>2016-10-01</date><risdate>2016</risdate><volume>70</volume><spage>32</spage><epage>40</epage><pages>32-40</pages><issn>0010-440X</issn><eissn>1532-8384</eissn><coden>COPYAV</coden><abstract>Abstract Objectives Although the relationship of obsessive–compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. Methods We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive–compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. Results The mean score of OCSs for patients having at least one symptom was 13.43 (SD = 8.32). Higher OCSs predicted increased SF (B = 0.98, t = 2.41, df = 88, p = 0.018). This relationship was driven by the association of compulsions with job functioning (B = 0.074, t = 2.029, df = 88, p = 0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive–compulsive symptom (mean difference = 2.496, t = 3.732, df = 88, p < 0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. Conclusion There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27624421</pmid><doi>10.1016/j.comppsych.2016.06.009</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Aged Cognition Cognition & reasoning Employment Female Hospitalization Humans Illnesses Male Memory Middle Aged Obsessive-Compulsive Disorder - complications Obsessive-Compulsive Disorder - psychology Psychiatry Psychopathology Psychotropic drugs Schizophrenia Schizophrenia - complications Schizophrenic Psychology Social Behavior Social research Studies Young Adult |
title | Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia |
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